CLPS anticorps (AA 18-112)

N° du produit ABIN6138743

Détail du produit anti-CLPS anticorps

Antigène: CLPS (Colipase, Pancreatic (CLPS))

Épitope: AA 18-112

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLPS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: APGPRGIIIN LENGELCMNS AQCKSNCCQH SSALGLARCT SMASENSECS VKTLYGIYYK CPCERGLTCE GDKTIVGSIT NTNFGICHDA GRSKQ

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 18-112 of human CLPS (NP_001823.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CLPS

Antigène: CLPS (Colipase, Pancreatic (CLPS))

Autre désignation: CLPS (CLPS Produits)

Synonymes: anticorps CLPS, anticorps 2200003J09Rik, anticorps COLQ, anticorps colipase, anticorps colipase, pancreatic, anticorps CLPS, anticorps Clps

Sujet: The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.,CLPS,colipase,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Lipases,Cardiovascular,Lipids,CLPS

Poids moléculaire: 11 kDa

ID gène: 1208

UniProt: P04118

Pathways: Lipid Metabolism