COL11A2 anticorps (AA 210-380)

N° du produit ABIN6138835

Détail du produit anti-COL11A2 anticorps

Antigène: COL11A2 (Collagen, Type XI, alpha 2 (COL11A2))

Épitope: AA 210-380

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COL11A2 est non-conjugé

Application: Western Blotting (WB)

Séquence: IVPGVQAAYE SCEQKELECE GGQRERPQNQ QPHRAQRSPQ QQPSRLHRPQ NQEPQSQPTE SLYYDYEPPY YDVMTTGTTP DYQDPTPGEE EEILESSLLP PLEEEQTDLQ VPPTADRFQA EEYGEGGTDP PEGPYDYTYG YGDDYREETE LGPALSAETA HSGAAAHGPR G

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 210-380 of human COL11A2 (NP_542411.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur COL11A2

Antigène: COL11A2 (Collagen, Type XI, alpha 2 (COL11A2))

Autre désignation: COL11A2 (COL11A2 Produits)

Synonymes: anticorps col11a2, anticorps MGC89039, anticorps COL11A2, anticorps RING3, anticorps DFNA13, anticorps DFNB53, anticorps FBCG2, anticorps HKE5, anticorps PARP, anticorps STL3, anticorps collagen, type XI, alpha 2, anticorps collagen type XI alpha 2 chain, anticorps bromodomain containing 2, anticorps col11a2, anticorps COL11A2, anticorps BRD2, anticorps Col11a2

Sujet: This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.,COL11A2,DFNA13,DFNB53,FBCG2,HKE5,PARP,STL3,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Extracellular Matrix,Collagen,Bone,Neuroscience,COL11A2

Poids moléculaire: 31 kDa/159-171 kDa

ID gène: 1302

UniProt: P13942

Pathways: Signalisation RTK, Sensory Perception of Sound, Chromatin Binding