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COPS2 anticorps (AA 1-310)

COPS2 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6138877
  • Antigène Voir toutes COPS2 Anticorps
    COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))
    Épitope
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-310
    Reactivité
    • 54
    • 46
    • 42
    • 10
    • 10
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 51
    • 2
    • 1
    Lapin
    Clonalité
    • 52
    • 2
    Polyclonal
    Conjugué
    • 25
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp COPS2 est non-conjugé
    Application
    • 47
    • 19
    • 18
    • 13
    • 10
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Séquence
    MSDMEDDFMC DDEEDYDLEY SEDSNSEPNV DLENQYYNSK ALKEDDPKAA LSSFQKVLEL EGEKGEWGFK ALKQMIKINF KLTNFPEMMN RYKQLLTYIR SAVTRNYSEK SINSILDYIS TSKQMDLLQE FYETTLEALK DAKNDRLWFK TNTKLGKLYL EREEYGKLQK ILRQLHQSCQ TDDGEDDLKK GTQLLEIYAL EIQMYTAQKN NKKLKALYEQ SLHIKSAIPH PLIMGVIREC GGKMHLREGE FEKAHTDFFE AFKNYDESGS PRRTTCLKYL VLANMLMKSG INPFDSQEAK PYKNDPEILA
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human COPS2 (NP_004227.1).
    Isotype
    IgG
    Top Product
    Discover our top product COPS2 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))
    Autre désignation
    COPS2 (COPS2 Produits)
    Synonymes
    anticorps COPS2, anticorps ALIEN, anticorps CSN2, anticorps SGN2, anticorps TRIP15, anticorps wu:fc05f05, anticorps wu:fc06g10, anticorps wu:fc60f04, anticorps wu:fl94f12, anticorps zgc:86624, anticorps csn2, anticorps Tb03.48O8.600, anticorps Trip15, anticorps AI315723, anticorps C85265, anticorps Csn2, anticorps Sgn2, anticorps alien-like, anticorps ATCSN2, anticorps CONSTITUTIVE PHOTOMORPHOGENIC 12, anticorps COP12, anticorps FUSCA 12, anticorps T20P8.4, anticorps T20P8_4, anticorps COP9 signalosome subunit 2, anticorps COP9 signalosome subunit 2 L homeolog, anticorps COP9 signalosome complex subunit 2, anticorps COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis), anticorps proteasome family protein, anticorps COPS2, anticorps cops2, anticorps cops2.L, anticorps Tb927.3.2320, anticorps AOR_1_576084, anticorps PTRG_07106, anticorps LOC100283498, anticorps Cops2, anticorps csn-2, anticorps FUS12
    Sujet
    Essential component of the COP9 signalosome complex (CSN, a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.,COPS2,ALIEN,CSN2,SGN2,TRIP15,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,COPS2
    Poids moléculaire
    51 kDa/52 kDa
    ID gène
    9318
    UniProt
    P61201
    Pathways
    Cycle Cellulaire
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