COPS5 anticorps (AA 1-334)

N° du produit ABIN6138883

Détail du produit anti-COPS5 anticorps

Antigène: COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))

Épitope: AA 1-334

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COPS5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: MAASGSGMAQ KTWELANNMQ EAQSIDEIYK YDKKQQQEIL AAKPWTKDHH YFKYCKISAL ALLKMVMHAR SGGNLEVMGL MLGKVDGETM IIMDSFALPV EGTETRVNAQ AAAYEYMAAY IENAKQVGRL ENAIGWYHSH PGYGCWLSGI DVSTQMLNQQ FQEPFVAVVI DPTRTISAGK VNLGAFRTYP KGYKPPDEGP SEYQTIPLNK IEDFGVHCKQ YYALEVSYFK SSLDRKLLEL LWNKYWVNTL SSSSLLTNAD YTTGQVFDLS EKLEQSEAQL GRGSFMLGLE THDRKSEDKL AKATRDSCKT TIEAIHGLMS QVIKDKLFNQ INIS

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human JAB1/CSN5/JAB1/CSN5/COPS5 (NP_006828.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur COPS5

Antigène: COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))

Autre désignation: COPS5 (COPS5 Produits)

Synonymes: anticorps BcDNA.LD14392, anticorps BcDNA:LD14392, anticorps CG14884, anticorps CH5, anticorps CSN-5, anticorps Csn5, anticorps DCH5, anticorps Dch5, anticorps Dmel\\CG14884, anticorps JAB1, anticorps JAB1/CSN5, anticorps Jab1, anticorps JadBp, anticorps csn5, anticorps dch5, anticorps jab1/csn5, anticorps l(3)89Cf, anticorps l(3)L4032, anticorps l(3)M203, anticorps quo, anticorps COPS5, anticorps MGC76063, anticorps AI303502, anticorps CSN5, anticorps Mov34, anticorps Sgn5, anticorps zgc:73130, anticorps MOV-34, anticorps SGN5, anticorps COP9 signalosome subunit 5, anticorps COP9 signalosome complex subunit 5, anticorps COP9 signalosome subunit 5 S homeolog, anticorps CSN5, anticorps COPS5, anticorps cops5, anticorps CpipJ_CPIJ012314, anticorps Bm1_46585, anticorps VDBG_06932, anticorps LOAG_01443, anticorps csn5, anticorps Cops5, anticorps cops5.S, anticorps csn-5

Sujet: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors.,COPS5,CSN5,JAB1,MOV-34,SGN5,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Ubiquitin,COPS5

Poids moléculaire: 37 kDa

ID gène: 10987

UniProt: Q92905

Pathways: Cycle Cellulaire