CD35 anticorps (AA 420-550)
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- Antigène Voir toutes CD35 (CR1) Anticorps
- CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))
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Épitope
- AA 420-550
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CD35 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Séquence
- FCPSPPVIPN GRHTGKPLEV FPFGKTVNYT CDPHPDRGTS FDLIGESTIR CTSDPQGNGV WSSPAPRCGI LGHCQAPDHF LFAKLKTQTN ASDFPIGTSL KYECRPEYYG RPFSITCLDN LVWSSPKDVC K
- Réactivité croisée
- Humain
- Attributs du produit
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 420-550 of human CD35/CD35/CR1 (NP_000642.3).
- Isotype
- IgG
- Top Product
- Discover our top product CR1 Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))
- Autre désignation
- CR1 (CR1 Produits)
- Sujet
- This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants, encoding different isoforms, have been characterized. Additional allele specific isoforms, including a secreted form, have been described but have not been fully characterized.,CR1,C3BR,C4BR,CD35,KN,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,CR1
- Poids moléculaire
- 223 kDa
- ID gène
- 1378
- UniProt
- P17927
- Pathways
- Système du Complément, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity
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