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CRYAA anticorps (AA 1-173)

CRYAA Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6139072
  • Antigène Voir toutes CRYAA Anticorps
    CRYAA (Crystallin, alpha A (CRYAA))
    Épitope
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    AA 1-173
    Reactivité
    • 45
    • 17
    • 16
    • 3
    • 1
    Humain
    Hôte
    • 27
    • 18
    • 1
    Lapin
    Clonalité
    • 27
    • 19
    Polyclonal
    Conjugué
    • 20
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CRYAA est non-conjugé
    Application
    • 34
    • 27
    • 17
    • 11
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    MDVTIQHPWF KRTLGPFYPS RLFDQFFGEG LFEYDLLPFL SSTISPYYRQ SLFRTVLDSG ISEVRSDRDK FVIFLDVKHF SPEDLTVKVQ DDFVEIHGKH NERQDDHGYI SREFHRRYRL PSNVDQSALS CSLSADGMLT FCGPKIQTGL DATHAERAIP VSREEKPTSA PSS
     Réactivité croisée
    Humain, Souris, Rat, Poisson zèbre (Danio rerio)
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human CRYAA (NP_000385.1).
    Isotype
    IgG
    Top Product
    Discover our top product CRYAA Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    CRYAA (Crystallin, alpha A (CRYAA))
    Autre désignation
    CRYAA (CRYAA Produits)
    Synonymes
    anticorps CRYA1, anticorps CTRCT9, anticorps HSPB4, anticorps AI323437, anticorps Acry-1, anticorps Crya-1, anticorps Crya1, anticorps DAcry-1, anticorps lop18, anticorps alpha-a-crystallin, anticorps cryaa-A, anticorps CRYAA, anticorps wu:fc06h04, anticorps zgc:92036, anticorps HspB4, anticorps crystallin alpha A, anticorps crystallin, alpha A, anticorps alphaA-crystallin, anticorps alpha-crystallin A chain-like, anticorps crystallin alpha A S homeolog, anticorps alpha-crystallin A chain, anticorps CRYAA, anticorps Cryaa, anticorps CpipJ_CPIJ005646, anticorps cryaa, anticorps LOC100384978, anticorps cryaa.S, anticorps LOC458589, anticorps LOC102724652
    Sujet
    Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits, the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alpha-A and alpha-B gene products are differentially expressed, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Defects in this gene cause autosomal dominant congenital cataract (ADCC).,CRYAA,CRYA1,CTRCT9,HSPB4,Signal Transduction,Neuroscience,Cell Type Marker,CRYAA
    Poids moléculaire
    19 kDa
    ID gène
    1409
    UniProt
    P02489
    Pathways
    M Phase
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