Exportin 2 anticorps (AA 50-150)

N° du produit ABIN6139091

Détail du produit anti-Exportin 2 anticorps

Antigène: Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

Épitope: AA 50-150

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Exportin 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: LEKSQDNVIK VCASVTFKNY IKRNWRIVED EPNKICEADR VAIKANIVHL MLSSPEQIQK QLSDAISIIG REDFPQKWPD LLTEMVNRFQ SGDFHVINGV L

Réactivité croisée: Humain, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Exportin 2 (XPO2) (NP_001243064.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Exportin 2

Antigène: Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

Autre désignation: CSE1L (CSE1L Produits)

Synonymes: anticorps BcDNA:LD14270, anticorps CAS, anticorps CG13281, anticorps Dcas, anticorps Dmel\\CG13281, anticorps cas, anticorps dcas, anticorps l(2)k03902, anticorps CSE1L, anticorps XPO2, anticorps Exportin-2, anticorps DKFZp459E1929, anticorps 2610100P18Rik, anticorps AA407533, anticorps Capts, anticorps Cas, anticorps Xpo2, anticorps xpo2, anticorps CSE1, anticorps CAS/CSE1 segregation protein, anticorps chromosome segregation 1 like, anticorps exportin-2, anticorps chromosome segregation 1-like (S. cerevisiae), anticorps CSE1 chromosome segregation 1-like (yeast), anticorps CSE1 chromosome segregation 1-like L homeolog, anticorps Cas, anticorps CSE1L, anticorps LOC100542094, anticorps cse1l, anticorps Cse1l, anticorps cse1l.L

Sujet: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene.,CSE1L,CAS,CSE1,XPO2,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,CSE1L

Poids moléculaire: 22 kDa/103 kDa/107 kDa/110 kDa

ID gène: 1434

UniProt: P55060

Pathways: Protein targeting to Nucleus