Cathepsin L anticorps (AA 114-333)

N° du produit ABIN6139235

Détail du produit anti-Cathepsin L anticorps

Antigène: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Épitope: AA 114-333

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin L est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: APRSVDWREK GYVTPVKNQG QCGSCWAFSA TGALEGQMFR KTGRLISLSE QNLVDCSGPQ GNEGCNGGLM DYAFQYVQDN GGLDSEESYP YEATEESCKY NPKYSVANDT GFVDIPKQEK ALMKAVATVG PISVAIDAGH ESFLFYKEGI YFEPDCSSED MDHGVLVVGY GFESTESDNN KYWLVKNSWG EEWGMGGYVK MAKDRRNHCG IASAASYPTV

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 114-333 of human Cathepsin L/V/K/H (NP_001903.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Cathepsin L

Antigène: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Autre désignation: CTSL (CTSL1 Produits)

Synonymes: anticorps CATL, anticorps CTSL1, anticorps MEP, anticorps 1190035F06Rik, anticorps Ctsl1, anticorps fs, anticorps nkt, anticorps CATHL, anticorps CatL, anticorps Ctsl, anticorps CTSL, anticorps mep, anticorps catl, anticorps ctsl, anticorps cpl-1, anticorps MGC80629, anticorps MGC107932, anticorps LOC663234, anticorps 26-29-p, anticorps Cp1, anticorps si:dkey-121a11.6, anticorps CTSV, anticorps catL, anticorps cb15, anticorps ctsl1b, anticorps hgg1, anticorps wu:fb30g09, anticorps zgc:92089, anticorps cathepsin L, anticorps cathepsin V, anticorps cathepsin L L homeolog, anticorps cathepsin L1, anticorps Cathepsin L1, anticorps Cathepsin L, anticorps testin gene, anticorps cathepsin 12, anticorps cathepsin Lb, anticorps cathepsin L.1, anticorps CTSL, anticorps Ctsl, anticorps CTSV, anticorps ctsl.L, anticorps ctsl, anticorps LOC100008830, anticorps catl1, anticorps 26-29-p, anticorps catl, anticorps Tsp_11596, anticorps Testin, anticorps cts12, anticorps LOC102156614, anticorps ctslb, anticorps ctsl.1

Sujet: The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.,CTSL,CATL,CTSL1,MEP,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Extracellular Matrix,Neuroscience,CTSL

Poids moléculaire: 37 kDa

ID gène: 1514

UniProt: P07711

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades