Cullin 5 anticorps (AA 1-300)

N° du produit ABIN6139259

Détail du produit anti-Cullin 5 anticorps

Antigène: Cullin 5 (CUL5)

Épitope: AA 1-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cullin 5 est non-conjugé

Application: Western Blotting (WB)

Séquence: MATSNLLKNK GSLQFEDKWD FMRPIVLKLL RQESVTKQQW FDLFSDVHAV CLWDDKGPAK IHQALKEDIL EFIKQAQARV LSHQDDTALL KAYIVEWRKF FTQCDILPKP FCQLEITLMG KQGSNKKSNV EDSIVRKLML DTWNESIFSN IKNRLQDSAM KLVHAERLGE AFDSQLVIGV RESYVNLCSN PEDKLQIYRD NFEKAYLDST ERFYRTQAPS YLQQNGVQNY MKYADAKLKE EEKRALRYLE TRRECNSVEA LMECCVNALV TSFKETILAE CQGMIKRNET EKLHLMFSLM

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CUL5 (NP_003469.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Cullin 5

Antigène: Cullin 5 (CUL5)

Autre désignation: CUL5 (CUL5 Produits)

Synonymes: anticorps cul5, anticorps wu:fd17d09, anticorps wu:fi20h12, anticorps xx:11fd17d09, anticorps zgc:66185, anticorps Xcullin5, anticorps CG1401, anticorps CUL5, anticorps Cul5, anticorps Cullin 5, anticorps Cullin5, anticorps Dmel\\CG1401, anticorps cul-5, anticorps vacm-1, anticorps vacm1, anticorps VACM-1, anticorps VACM1, anticorps 4921514I20Rik, anticorps 8430423K24Rik, anticorps AI852817, anticorps C030032G03Rik, anticorps C330021I08Rik, anticorps Cullin-5, anticorps cullin 5a, anticorps cullin 5 L homeolog, anticorps Cullin 5, anticorps cullin 5, anticorps Cullin-5, anticorps cul5a, anticorps cul5.L, anticorps Cul5, anticorps CUL5, anticorps cul5, anticorps cul-5

Sujet: Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1 seems to direct ubiquitination of JAK2. ECS(KLHDC1 complex is part of the DesCEND (destruction via C-end degrons pathway and mediates ubiquitination and degradation of truncated SELENOS selenoprotein produced by failed UGA/Sec decoding, which ends with a glycine. May form a cell surface vasopressin receptor.,CUL5,CUL-5,VACM-1,VACM1,cullin-5,Cell Biology & Developmental Biology,Apoptosis,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,CUL5

Poids moléculaire: 90 kDa

ID gène: 8065

UniProt: Q93034

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development