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DERL1 anticorps (AA 182-251)

DERL1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6139538
  • Antigène Voir toutes DERL1 Anticorps
    DERL1 (Der1-Like Domain Family, Member 1 (DERL1))
    Épitope
    • 15
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 182-251
    Reactivité
    • 33
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 32
    • 1
    Lapin
    Clonalité
    • 32
    • 1
    Polyclonal
    Conjugué
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DERL1 est non-conjugé
    Application
    • 17
    • 13
    • 13
    • 12
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    LYFFLMFRYP MDLGGRNFLS TPQFLYRWLP SRRGGVSGFG VPPASMRRAA DQNGGGGRHN WGQGFRLGDQ
     Réactivité croisée
    Humain, Souris
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 182-251 of human DERL1 (NP_077271.1).
    Isotype
    IgG
    Top Product
    Discover our top product DERL1 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    DERL1 (Der1-Like Domain Family, Member 1 (DERL1))
    Autre désignation
    DERL1 (DERL1 Produits)
    Sujet
    The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms.,DERL1,DER-1,DER1,derlin-1,Signal Transduction,Neuroscience,Neurodegenerative Diseases,DERL1
    Poids moléculaire
    26 kDa/28 kDa
    ID gène
    79139
    UniProt
    Q9BUN8
    Pathways
    ER-Nucleus Signaling
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