DERL1 anticorps (AA 182-251)

N° du produit ABIN6139538

Détail du produit anti-DERL1 anticorps

Antigène: DERL1 (Der1-Like Domain Family, Member 1 (DERL1))

Épitope: AA 182-251

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DERL1 est non-conjugé

Application: Western Blotting (WB)

Séquence: LYFFLMFRYP MDLGGRNFLS TPQFLYRWLP SRRGGVSGFG VPPASMRRAA DQNGGGGRHN WGQGFRLGDQ

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 182-251 of human DERL1 (NP_077271.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DERL1

Antigène: DERL1 (Der1-Like Domain Family, Member 1 (DERL1))

Autre désignation: DERL1 (DERL1 Produits)

Sujet: The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms.,DERL1,DER-1,DER1,derlin-1,Signal Transduction,Neuroscience,Neurodegenerative Diseases,DERL1

Poids moléculaire: 26 kDa/28 kDa

ID gène: 79139

UniProt: Q9BUN8

Pathways: ER-Nucleus Signaling