Endothelin 3 anticorps (AA 17-187)

N° du produit ABIN6139934

Détail du produit anti-Endothelin 3 anticorps

Antigène: Endothelin 3 (EDN3)

Épitope: AA 17-187

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Endothelin 3 est non-conjugé

Application: Western Blotting (WB)

Séquence: AGFVPCSQSG DAGRRGVSQA PTAARSEGDC EETVAGPGEE TVAGPGEGTV APTALQGPSP GSPGQEQAAE GAPEHHRSRR CTCFTYKDKE CVYYCHLDII WINTPEQTVP YGLSNYRGSF RGKRSAGPLP GNLQLSHRPH LRCACVGRYD KACLHFCTQT LDVSSNSRTA E

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 17-187 of human EDN3 (NP_996917.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Endothelin 3

Antigène: Endothelin 3 (EDN3)

Autre désignation: EDN3 (EDN3 Produits)

Synonymes: anticorps et-3, anticorps EDN3, anticorps ET-3, anticorps ET3, anticorps HSCR4, anticorps PPET3, anticorps WS4B, anticorps 114CH19, anticorps ls, anticorps tmgc48, anticorps Et3, anticorps RGD1564825, anticorps preproET-3, anticorps endothelin-3 L homeolog, anticorps endothelin 3, anticorps edn3.L, anticorps EDN3, anticorps Edn3

Sujet: The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms.,EDN3,ET-3,ET3,HSCR4,PPET3,WS4B,Cancer,Invasion and Metastasis,Signal Transduction,Neuroscience,EDN3

Poids moléculaire: 23 kDa/25 kDa

ID gène: 1908

UniProt: P14138

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones