EED anticorps (AA 1-300)

N° du produit ABIN6139942

Détail du produit anti-EED anticorps

Antigène: EED (Embryonic Ectoderm Development (EED))

Épitope: AA 1-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EED est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Séquence: MSEREVSTAP AGTDMPAAKK QKLSSDENSN PDLSGDENDD AVSIESGTNT ERPDTPTNTP NAPGRKSWGK GKWKSKKCKY SFKCVNSLKE DHNQPLFGVQ FNWHSKEGDP LVFATVGSNR VTLYECHSQG EIRLLQSYVD ADADENFYTC AWTYDSNTSH PLLAVAGSRG IIRIINPITM QCIKHYVGHG NAINELKFHP RDPNLLLSVS KDHALRLWNI QTDTLVAIFG GVEGHRDEVL SADYDLLGEK IMSCGMDHSL KLWRINSKRM MNAIKESYDY NPNKTNRPFI SQKIHFPDFS

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human EED (NP_694536.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IP,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-EED (ABIN6139942)

Tang, Guo, Zhu, Huang, Liu, Cai, Yu, Wang: "Metformin inhibits ovarian cancer via decreasing H3K27 trimethylation." dans: International journal of oncology, Vol. 52, Issue 6, pp. 1899-1911, (2018) (PubMed).

Détails sur EED

Antigène: EED (Embryonic Ectoderm Development (EED))

Autre désignation: EED (EED Produits)

Synonymes: anticorps Xeed, anticorps heed, anticorps wait1, anticorps EED, anticorps HEED, anticorps WAIT1, anticorps zgc:112509, anticorps Xeed-B, anticorps eed, anticorps psXEED, anticorps ENSMUSG00000039373, anticorps l(7)5Rn, anticorps l7Rn5, anticorps lusk, anticorps Xeed-A, anticorps embryonic ectoderm development, anticorps embryonic ectoderm development S homeolog, anticorps microRNA 6755, anticorps embryonic ectoderm development L homeolog, anticorps eed, anticorps EED, anticorps eed.S, anticorps MIR6755, anticorps Eed, anticorps eed.L

Sujet: This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene.,EED,HEED,WAIT1,Epigenetics & Nuclear Signaling,Chromatin Remodeling,EED

Poids moléculaire: 45 kDa/50 kDa/53 kDa

ID gène: 8726

UniProt: O75530