EZH2 anticorps (AA 1-250)

N° du produit ABIN6140393

Détail du produit anti-EZH2 anticorps

Antigène: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Épitope: AA 1-250

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EZH2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: MGQTGKKSEK GPVCWRKRVK SEYMRLRQLK RFRRADEVKS MFSSNRQKIL ERTEILNQEW KQRRIQPVHI LTSVSSLRGT RECSVTSDLD FPTQVIPLKT LNAVASVPIM YSWSPLQQNF MVEDETVLHN IPYMGDEVLD QDGTFIEELI KNYDGKVHGD RECGFINDEI FVELVNALGQ YNDDDDDDDG DDPEEREEKQ KDLEDHRDDK ESRPPRKFPS DKIFEAISSM FPDKGTAEEL KEKYKELTEQ

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human EZH2/KMT6 (NP_001190176.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-EZH2 (ABIN6140393)

Cao, Liu, Yue, Liu, Pei, Gu, Wang, Jia: "Iron chelation inhibits cancer cell growth and modulates global histone methylation status in colorectal cancer." dans: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, Vol. 31, Issue 5, pp. 797-805, (2018) (PubMed).

Détails sur EZH2

Antigène: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Autre désignation: EZH2 (EZH2 Produits)

Synonymes: anticorps ENX-1, anticorps ENX1, anticorps EZH1, anticorps EZH2b, anticorps KMT6, anticorps KMT6A, anticorps WVS, anticorps WVS2, anticorps eya2, anticorps im:7149338, anticorps zgc:136376, anticorps zgc:152758, anticorps EZH2, anticorps enx-1, anticorps enx1, anticorps ezh1, anticorps kmt6, anticorps xez, anticorps Enx-1, anticorps Enx1h, anticorps mKIAA4065, anticorps ezh2, anticorps olezh2, anticorps enhancer of zeste 2 polycomb repressive complex 2 subunit, anticorps enhancer of zeste 2 polycomb repressive complex 2 subunit L homeolog, anticorps enhancer of zeste 2 polycomb repressive complex 2 subunit S homeolog, anticorps EZH2, anticorps ezh2, anticorps Ezh2, anticorps ezh2.L, anticorps ezh2.S

Sujet: This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.,ENX-1,ENX1,EZH1,EZH2b,KMT6,KMT6A,WVS,WVS2,EZH2,KMT6 / EZH2,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Methylation,Chromatin Remodeling,Cancer,Tumor biomarkers,EZH2

Poids moléculaire: 79 kDa/81 kDa/84 kDa/85 kDa/86 kDa

ID gène: 2146

UniProt: Q15910

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation