anticorps FAAP250, anticorps KIAA1596, anticorps AI427100, anticorps C730036B14Rik, anticorps D12Ertd364e, anticorps Fanconi anemia complementation group M, anticorps hypothetical protein, anticorps Fanconi anemia, complementation group M, anticorps FANCM, anticorps PGTG_17854, anticorps Fancm
Sujet
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group M. Alternative splicing results in multiple transcript variants.,FANCM,FAAP250,KIAA1596,Epigenetics & Nuclear Signaling,DNA Damage & Repair,FANCM