FN1
Reactivité: Humain
ELISA, IHC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB,1:500 - 1:2000
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Xie, Zhang, Wang, Zhao, Zhang, Yao, Hur, Yeh, Pang, Zheng, Fan, Kong, Wang, Chiu, Zhou: "Matrix stiffness determines the phenotype of vascular smooth muscle cell in vitro and in vivo: Role of DNA methyltransferase 1." dans: Biomaterials, Vol. 155, pp. 203-216, (2018) (PubMed).
Cai, Ma, Xiao, Wu, Li, Liu, Qiu, Zhang: "High doses of baicalin induces kidney injury and fibrosis through regulating TGF-β/Smad signaling pathway." dans: Toxicology and applied pharmacology, Vol. 333, pp. 1-9, (2017) (PubMed).
This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined.,FN1,CIG,ED-B,FINC,FN,FNZ,GFND,GFND2,LETS,MSF,fibronectin,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Stem Cells,Mesenchymal Stem Cells,Neural Stem Cells,Cardiovascular,Angiogenesis,FN1