FOXO3 anticorps (AA 394-672)

N° du produit ABIN6140755

Détail du produit anti-FOXO3 anticorps

Antigène: FOXO3 (Forkhead Box O3 (FOXO3))

Épitope: AA 394-672

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXO3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: ALPPSQPSPP GGLMQRGSSF PYTAKSSGLG SPTGSFNSTV FGPSSLNSLR QSPMQTIQEN RPATFSSVSH YGNQTLQDLL ASDSLSHSDV MMTQSDPLMS QASTAVSAQN ARRNVMLRND PMMSFAAQPT QGSLVNQNLL HHQHQTQGAL GGSRALSNSV SNMGLSDSSS LGSAKHQQQS PASQSMQTLS DSLSGSSLYS ASANLPVMGH DKFPSDLDLD MFNGSLECDM ESIIRSELMD ADGLDFNFDS LISTQNVVGL NVGNFTGAKQ ASSQSWVPG

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 394-672 of mouse FOXO3A (NP_062714.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-FOXO3 (ABIN6140755)

Li, Chan, Yu, Bei, Chen, Zhou, Cheng, Chen, Ziegler, Rowe, Das, Xiao: "miR-29b contributes to multiple types of muscle atrophy." dans: Nature communications, Vol. 8, pp. 15201, (2018) (PubMed).

Liu, Cai, Hu, Mei, Zhang, Ouyang, Wang, Zhang, Xiao: "Forkhead Transcription Factor 3a (FOXO3a) Modulates Hypoxia Signaling via Up-regulation of the von Hippel-Lindau Gene (VHL)." dans: The Journal of biological chemistry, Vol. 291, Issue 49, pp. 25692-25705, (2017) (PubMed).

Yang, Wang, Xiong, Kong, Qiu, Shen, Huang: "Activation of SIRT3 attenuates triptolide-induced toxicity through closing mitochondrial permeability transition pore in cardiomyocytes." dans: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 34, pp. 128-137, (2017) (PubMed).

Détails sur FOXO3

Antigène: FOXO3 (Forkhead Box O3 (FOXO3))

Autre désignation: FOXO3 (FOXO3 Produits)

Synonymes: anticorps AF6q21, anticorps FKHRL1, anticorps FKHRL1P2, anticorps FOXO2, anticorps FOXO3A, anticorps zgc:92176, anticorps wu:fb50g02, anticorps wu:fi33f07, anticorps Fkhrl1, anticorps Foxo3a, anticorps FoxO3A, anticorps 1110048B16Rik, anticorps 2010203A17Rik, anticorps C76856, anticorps Fkhr2, anticorps FOXO-3, anticorps FOXO3, anticorps foxo3a, anticorps xfoxo3, anticorps foxO3, anticorps foxO, anticorps fkhr, anticorps foxo5, anticorps wu:fj65a12, anticorps zFkhr, anticorps forkhead box O3, anticorps forkhead box O3A, anticorps forkhead box O3 L homeolog, anticorps forkhead box O3b, anticorps FOXO3, anticorps foxo3a, anticorps Foxo3, anticorps foxo3.L, anticorps foxo3, anticorps foxO3, anticorps foxo3b

Sujet: This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.,FOXO3,AF6q21,FKHRL1,FKHRL1P2,FOXO2,FOXO3A,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Autophagy,Cell Cycle,G1/S Checkpoint,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,FOXO3

Poids moléculaire: 71 kDa

ID gène: 56484

UniProt: Q9WVH4

Pathways: Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis