GAB2 anticorps (AA 377-676)

N° du produit ABIN6140869

Détail du produit anti-GAB2 anticorps

Antigène: GAB2 (GRB2-Associated Binding Protein 2 (GAB2))

Épitope: AA 377-676

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GAB2 est non-conjugé

Application: Western Blotting (WB)

Séquence: ENSRSVAATI PRRNTLPAMD NSRLHRASSC ETYEYPQRGG ESAGRSAESM SDGVGSFLPG KMIVGRSDST NSEDNYVPMN PGSSTLLAME RAGDNSQSVY IPMSPGAHHF DSLGYPSTTL PVHRGPSRGS EIQPPPVNRN LKPDRKAKPT PLDLRNNTVI DELPFKSPIT KSWSRANHTF NSSSSQYCRP ISTQSITSTD SGDSEENYVP MQNPVSASPV PSGTNSPAPK KSTGSVDYLA LDFQPSSPSP HRKPSTSSVT SDEKVDYVQV DKEKTQALQN TMQEWTDVRQ SSEPSKGAKL

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 377-676 of human GAB2 (NP_536739.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GAB2

Antigène: GAB2 (GRB2-Associated Binding Protein 2 (GAB2))

Autre désignation: GAB2 (GAB2 Produits)

Synonymes: anticorps GAB2, anticorps AI463667, anticorps D130058I17Rik, anticorps p97, anticorps GRB2 associated binding protein 2, anticorps GRB2-associated binding protein 2, anticorps growth factor receptor bound protein 2-associated protein 2, anticorps GAB2, anticorps gab2, anticorps Gab2

Sujet: This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.,GAB2,Cancer,Signal Transduction,PI3K-Akt Signaling Pathway,ErbB-HER Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,GAB2

Poids moléculaire: 69 kDa/74 kDa

ID gène: 9846

UniProt: Q9UQC2

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, BCR Signaling, L'effet Warburg