GEN1 anticorps (AA 669-908)

N° du produit ABIN6141058

Détail du produit anti-GEN1 anticorps

Antigène: GEN1 (Gen Endonuclease Homolog 1 (GEN1))

Épitope: AA 669-908

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GEN1 est non-conjugé

Application: Western Blotting (WB)

Séquence: LQDLPLKERI FTKLSYPQDN LQPDVNLKTL SILSVKESCI ANSGSDCTSH LSKDLPGIPL QNESRDSKIL KGDQLLQEDY KVNTSVPYSV SNTVVKTCNV RPPNTALDHS RKVDMQTTRK ILMKKSVCLD RHSSDEQSAP VFGKAKYTTQ RMKHSSQKHN SSHFKESGHN KLSSPKIHIK ETEQCVRSYE TAENEESCFP DSTKSSLSSL QCHKKENNSG TCLDSPLPLR QRLKLRFQST

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 669-908 of human GEN1 (NP_872431.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GEN1

Antigène: GEN1 (Gen Endonuclease Homolog 1 (GEN1))

Autre désignation: GEN1 (GEN1 Produits)

Synonymes: anticorps 5830483C08Rik, anticorps Gen, anticorps RGD1559792, anticorps GEN1, Holliday junction 5' flap endonuclease, anticorps GEN1 Holliday junction 5' flap endonuclease, anticorps GEN1, anticorps Gen1

Sujet: This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family, whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions, which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition, this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants.,GEN1,Gen,Epigenetics & Nuclear Signaling,DNA Damage & Repair,GEN1

Poids moléculaire: 102 kDa

ID gène: 348654

UniProt: Q17RS7

Pathways: Réparation de l'ADN