Geminin anticorps (AA 1-209)
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- Antigène Voir toutes Geminin (GMNN) Anticorps
- Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
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Épitope
- AA 1-209
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Geminin est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- MNPSMKQKQE EIKENIKNSS VPRRTLKMIQ PSASGSLVGR ENELSAGLSK RKHRNDHLTS TTSSPGVIVP ESSENKNLGG VTQESFDLMI KENPSSQYWK EVAEKRRKAL YEALKENEKL HKEIEQKDNE IARLKKENKE LAEVAEHVQY MAELIERLNG EPLDNFESLD NQEFDSEEET VEDSLVEDSE IGTCAEGTVS SSTDAKPCI
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-209 of human GMNN (NP_056979.1).
- Isotype
- IgG
- Top Product
- Discover our top product GMNN Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Commentaires
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
- Autre désignation
- GMNN (GMNN Produits)
- Synonymes
- anticorps CG3183, anticorps Dm Geminin, anticorps Dm geminin, anticorps Dmel\\CG3183, anticorps Gem, anticorps Geminin, anticorps anon-WO0257455.1, anticorps gem, anticorps l(2)k14019, anticorps v(2)k09107, anticorps sb:cb254, anticorps zgc:66217, anticorps GB16871, anticorps GMNN, anticorps geminin, anticorps dyak_GLEANR_833, anticorps DyakGE24654, anticorps GE24654, anticorps LOC100049517, anticorps AW546347, anticorps geminin, DNA replication inhibitor, anticorps CG3183 gene product from transcript CG3183-RA, anticorps geminin, anticorps GE24654 gene product from transcript GE24654-RA, anticorps GMNN, anticorps geminin, anticorps gmnn, anticorps LOC410093, anticorps Dyak\geminin, anticorps Gmnn
- Sujet
- This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.,GMNN,Gem,MGORS6,geminin,Epigenetics & Nuclear Signaling,Cancer,Cell Biology & Developmental Biology,Cell Cycle,GMNN
- Poids moléculaire
- 23 kDa
- ID gène
- 51053
- UniProt
- O75496
- Pathways
- EGFR Signaling Pathway, DNA Replication
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