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Metabotropic Glutamate Receptor 4 anticorps (AA 33-290)

GRM4 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6141425
  • Antigène Voir toutes Metabotropic Glutamate Receptor 4 (GRM4) Anticorps
    Metabotropic Glutamate Receptor 4 (GRM4) (Glutamate Receptor, Metabotropic 4 (GRM4))
    Épitope
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 33-290
    Reactivité
    • 18
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 17
    • 1
    Lapin
    Clonalité
    • 18
    Polyclonal
    Conjugué
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Metabotropic Glutamate Receptor 4 est non-conjugé
    Application
    • 10
    • 9
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    KPKGHPHMNS IRIDGDITLG GLFPVHGRGS EGKPCGELKK EKGIHRLEAM LFALDRINND PDLLPNITLG ARILDTCSRD THALEQSLTF VQALIEKDGT EVRCGSGGPP IITKPERVVG VIGASGSSVS IMVANILRLF KIPQISYAST APDLSDNSRY DFFSRVVPSD TYQAQAMVDI VRALKWNYVS TVASEGSYGE SGVEAFIQKS REDGGVCIAQ SVKIPREPKA GEFDKIIRRL LETSNARAVI IFANEDDI
     Réactivité croisée
    Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 33-290 of human GRM4 (NP_000832.1).
    Isotype
    IgG
    Top Product
    Discover our top product GRM4 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    Metabotropic Glutamate Receptor 4 (GRM4) (Glutamate Receptor, Metabotropic 4 (GRM4))
    Autre désignation
    GRM4 (GRM4 Produits)
    Synonymes
    anticorps GPRC1D, anticorps MGLUR4, anticorps mGlu4, anticorps Gprc1d, anticorps mGluR4, anticorps glutamate metabotropic receptor 4, anticorps glutamate receptor, metabotropic 4, anticorps GRM4, anticorps Grm4
    Sujet
    L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene.,GRM4,GPRC1D,MGLUR4,mGlu4,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Apoptosis,Neuroscience,GRM4
    Poids moléculaire
    83 kDa/86 kDa/87 kDa/88 kDa/101 kDa
    ID gène
    2914
    UniProt
    Q14833
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