HECTD1 anticorps (AA 2518-2610)

N° du produit ABIN6141706

Détail du produit anti-HECTD1 anticorps

Antigène: HECTD1 (HECT Domain Containing 1 (HECTD1))

Épitope: AA 2518-2610

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HECTD1 est non-conjugé

Application: Western Blotting (WB)

Séquence: PGFLRFVRVL CGMSSDERKA FLQFTTGCST LPPGGLANLH PRLTVVRKVD ATDASYPSVN TCVHYLKLPE YSSEEIMRER LLAATMEKGF HLN

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 2518-2610 of human HECTD1 (NP_056197.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur HECTD1

Antigène: HECTD1 (HECT Domain Containing 1 (HECTD1))

Autre désignation: HECTD1 (HECTD1 Produits)

Synonymes: anticorps RGD1561653, anticorps HECTD1, anticorps hectd1, anticorps MGC172681, anticorps A630086P08Rik, anticorps AI844876, anticorps b2b327Clo, anticorps opm, anticorps HECT domain E3 ubiquitin protein ligase 1, anticorps HECT domain containing E3 ubiquitin protein ligase 1, anticorps Hectd1, anticorps HECTD1, anticorps hectd1

Sujet: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates 'Lys-63'-linked polyubiquitination of HSP90AA1 which leads to its intracellular localization and reduced secretion. Negatively regulating HSP90AA1 secretion in cranial mesenchyme cells may impair their emigration and may be essential for the correct development of the cranial neural folds and neural tube closure.,HECTD1,EULIR,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,HECTD1

Poids moléculaire: 289 kDa

ID gène: 25831

UniProt: Q9ULT8

Pathways: Tube Formation, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2