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HSPA2 anticorps (AA 400-639)

HSPA2 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6142040
  • Antigène Voir toutes HSPA2 Anticorps
    HSPA2 (Heat Shock 70kDa Protein 2 (HSPA2))
    Épitope
    • 8
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 400-639
    Reactivité
    • 47
    • 25
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 38
    • 17
    Lapin
    Clonalité
    • 31
    • 24
    Polyclonal
    Conjugué
    • 29
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp HSPA2 est non-conjugé
    Application
    • 40
    • 15
    • 12
    • 8
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Séquence
    TPLSLGIETA GGVMTPLIKR NTTIPTKQTQ TFTTYSDNQS SVLVQVYEGE RAMTKDNNLL GKFDLTGIPP APRGVPQIEV TFDIDANGIL NVTAADKSTG KENKITITND KGRLSKDDID RMVQEAERYK SEDEANRDRV AAKNALESYT YNIKQTVEDE KLRGKISEQD KNKILDKCQE VINWLDRNQM AEKDEYEHKQ KELERVCNPI ISKLYQGGPG GGSGGGGSGA SGGPTIEEVD
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 400-639 of human HSPA2 (NP_068814.2).
    Isotype
    IgG
    Top Product
    Discover our top product HSPA2 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    HSPA2 (Heat Shock 70kDa Protein 2 (HSPA2))
    Autre désignation
    HSPA2 (HSPA2 Produits)
    Synonymes
    anticorps HSP70-2, anticorps HSP70-3, anticorps HSPA2, anticorps DKFZp468B217, anticorps 70kDa, anticorps HSP70.2, anticorps HSP70A2, anticorps Hsp70-2, anticorps Hspt70, anticorps Hst70, anticorps HSPA3, anticorps heat shock protein family A (Hsp70) member 2, anticorps heat shock protein Hsp20, anticorps heat shock 70kDa protein 2, anticorps heat shock protein 2, anticorps heat shock protein family A member 2, anticorps HSPA2, anticorps hspA2, anticorps Hspa2
    Sujet
    Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release. Plays a role in spermatogenesis. In association with SHCBP1L may participate in the maintenance of spindle integrity during meiosis in male germ cells (By similarity.,HSPA2,HSP70-2,HSP70-3,Cancer,Tumor biomarkers,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,HSPA2
    Poids moléculaire
    70 kDa
    ID gène
    3306
    UniProt
    P54652
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