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HUS1 anticorps (AA 1-280)

HUS1 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6142084
  • Antigène Voir toutes HUS1 Anticorps
    HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
    Épitope
    • 15
    • 8
    • 7
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-280
    Reactivité
    • 51
    • 28
    • 15
    Humain
    Hôte
    • 62
    • 4
    Lapin
    Clonalité
    • 65
    • 1
    Polyclonal
    Conjugué
    • 23
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HUS1 est non-conjugé
    Application
    • 31
    • 27
    • 13
    • 13
    • 9
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Séquence
    MKFRAKIVDG ACLNHFTRIS NMIAKLAKTC TLRISPDKLN FILCDKLANG GVSMWCELEQ ENFFNEFQME GVSAENNEIY LELTSENLSR ALKTAQNARA LKIKLTNKHF PCLTVSVELL SMSSSSRIVT HDIPIKVIPR KLWKDLQEPV VPDPDVSIYL PVLKTMKSVV EKMKNISNHL VIEANLDGEL NLKIETELVC VTTHFKDLGN PPLASESTHE DRNVEHMAEV HIDIRKLLQF LAGQQVNPTK ALCNIVNNKM VHFDLLHEDV SLQYFIPALS
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human HUS1 (NP_004498.1).
    Isotype
    IgG
    Top Product
    Discover our top product HUS1 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
    Autre désignation
    HUS1 (HUS1 Produits)
    Synonymes
    anticorps hHUS1, anticorps mHus1, anticorps XHus1, anticorps hus1, anticorps HUS1 checkpoint clamp component, anticorps checkpoint clamp complex protein Hus1, anticorps HUS1 checkpoint clamp component L homeolog, anticorps HUS1, anticorps Hus1, anticorps hus1, anticorps hus1.L
    Sujet
    The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants.,HUS1,hHUS1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Signal Transduction,Kinase,HUS1
    Poids moléculaire
    29 kDa/31 kDa
    ID gène
    3364
    UniProt
    O60921
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