IDH2 anticorps (AA 193-452)
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- Antigène Voir toutes IDH2 Anticorps
- IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
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Épitope
- AA 193-452
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IDH2 est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)
- Séquence
- KMVFTPKDGS GVKEWEVYNF PAGGVGMGMY NTDESISGFA HSCFQYAIQK KWPLYMSTKN TILKAYDGRF KDIFQEIFDK HYKTDFDKNK IWYEHRLIDD MVAQVLKSSG GFVWACKNYD GDVQSDILAQ GFGSLGLMTS VLVCPDGKTI EAEAAHGTVT RHYREHQKGR PTSTNPIASI FAWTRGLEHR GKLDGNQDLI RFAQMLEKVC VETVESGAMT KDLAGCIHGL SNVKLNEHFL NTTDFLDTIK SNLDRALGRQ
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 193-452 of human IDH2 (NP_002159.2).
- Isotype
- IgG
- Top Product
- Discover our top product IDH2 Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000,IF,1:20 - 1:50,IP,1:50 - 1:200,ChIP,1:20 - 1:100
- Commentaires
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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Identification of proteins responsible for adriamycin resistance in breast cancer cells using proteomics analysis." dans: Scientific reports, Vol. 5, pp. 9301, (2016) (PubMed).
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Identification of proteins responsible for adriamycin resistance in breast cancer cells using proteomics analysis." dans: Scientific reports, Vol. 5, pp. 9301, (2016) (PubMed).
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- Antigène
- IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
- Autre désignation
- IDH2 (IDH2 Produits)
- Sujet
- Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.,IDH2,D2HGA2,ICD-M,IDH,IDHM,IDP,IDPM,mNADP-IDH,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,IDH2
- Poids moléculaire
- 45 kDa/50 kDa
- ID gène
- 3418
- UniProt
- P48735
- Pathways
- L'effet Warburg
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