IFI27 anticorps (AA 1-100)

N° du produit ABIN6142164

Détail du produit anti-IFI27 anticorps

Antigène: IFI27 (Interferon, alpha-Inducible Protein 27 (IFI27))

Épitope: AA 1-100

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFI27 est non-conjugé

Application: Western Blotting (WB)

Séquence: MEASALTSSA VTSVAKVVRV ASGSAVVLPL ARIATVVIGG VVAVPMVLSA MGFTAAGIAS SSIAAKMMSA AAIANGGGVA SGSLVATLQS LGATGLSGLT

Réactivité croisée: Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IFI27 (NP_005523.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IFI27

Antigène: IFI27 (Interferon, alpha-Inducible Protein 27 (IFI27))

Autre désignation: IFI27 (IFI27 Produits)

Synonymes: anticorps FAM14D, anticorps ISG12, anticorps ISG12A, anticorps P27, anticorps IRG1, anticorps Ifi27l, anticorps Ifi27l1, anticorps isg12(a), anticorps interferon alpha inducible protein 27, anticorps interferon, alpha-inducible protein 27, anticorps IFI27, anticorps Ifi27

Sujet: Probable adapter protein involved in different biological processes. Part of the signaling pathways that lead to apoptosis. Involved in type-I interferon-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9. Also functions in TNFSF10-induced apoptosis. May also have a function in the nucleus, where it may be involved in the interferon-induced negative regulation of the transcriptional activity of NR4A1, NR4A2 and NR4A3 through the enhancement of XPO1-mediated nuclear export of these nuclear receptors. May thereby play a role in the vascular response to injury (By similarity. In the innate immune response, has an antiviral activity towards hepatitis C virus/HCV. May prevent the replication of the virus by recruiting both the hepatitis C virus non-structural protein 5A/NS5A and the ubiquitination machinery via SKP2, promoting the ubiquitin-mediated proteasomal degradation of NS5A.,IFI27,FAM14D,ISG12,ISG12A,P27,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,IFI27

Poids moléculaire: 11 kDa

ID gène: 3429

UniProt: P40305

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Sensory Perception of Sound, Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Autophagy