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IGF2R anticorps (AA 2327-2491)

IGF2R Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6142247
  • Antigène Voir toutes IGF2R Anticorps
    IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
    Épitope
    • 16
    • 13
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2327-2491
    Reactivité
    • 88
    • 36
    • 19
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 67
    • 23
    Lapin
    Clonalité
    • 66
    • 24
    Polyclonal
    Conjugué
    • 46
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IGF2R est non-conjugé
    Application
    • 34
    • 33
    • 28
    • 23
    • 13
    • 13
    • 13
    • 11
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Séquence
    YKKERRETVI SKLTTCCRRS SNVSYKYSKV NKEEETDENE TEWLMEEIQL PPPRQGKEGQ ENGHITTKSV KALSSLHGDD QDSEDEVLTI PEVKVHSGRG AGAESSHPVR NAQSNALQER EDDRVGLVRG EKARKGKSSS AQQKTVSSTK LVSFHDDSDE DLLHI
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 2327-2491 of human Cation-independent M6PR (Cation-independent M6PR (IGF2R)) (NP_000867.2).
    Isotype
    IgG
    Top Product
    Discover our top product IGF2R Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
    Autre désignation
    IGF2R (IGF2R Produits)
    Synonymes
    anticorps CD222, anticorps CIMPR, anticorps M6P-R, anticorps MPR1, anticorps MPRI, anticorps AI661837, anticorps CI-MPR, anticorps M6P/IGF2R, anticorps Mpr300, anticorps mpri, anticorps cd222, anticorps cimpr, anticorps m6p-r, anticorps insulin like growth factor 2 receptor, anticorps insulin-like growth factor 2 receptor, anticorps IGF2R, anticorps Igf2r, anticorps igf2r
    Sujet
    This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele, however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611).,IGF2R,CD222,CI-M6PR,CIMPR,M6P-R,M6P/IGF2R,MPR 300,MPR1,MPR300,MPRI,Signal Transduction,Immunology & Inflammation,CD markers,Cell Intrinsic Innate Immunity Signaling Pathway,IGF2R
    Poids moléculaire
    274 kDa
    ID gène
    3482
    UniProt
    P11717
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