IL18BP anticorps (AA 31-194)

N° du produit ABIN6142329

Détail du produit anti-IL18BP anticorps

Antigène: IL18BP (Interleukin 18 Binding Protein (IL18BP))

Épitope: AA 31-194

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL18BP est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: TPVSQTTTAA TASVRSTKDP CPSQPPVFPA AKQCPALEVT WPEVEVPLNG TLSLSCVACS RFPNFSILYW LGNGSFIEHL PGRLWEGSTS RERGSTGTQL CKALVLEQLT PALHSTNFSC VLVDPEQVVQ RHVVLAQLWA GLRATLPPTQ EALPSSHSSP QQQG

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 31-194 of human IL18BP (NP_001138529.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IL18BP

Antigène: IL18BP (Interleukin 18 Binding Protein (IL18BP))

Autre désignation: IL18BP (IL18BP Produits)

Synonymes: anticorps IL18BP, anticorps IL-18BP, anticorps Igifbp, anticorps MC54L, anticorps IL18BPa, anticorps interleukin 18 binding protein, anticorps IL18BP, anticorps Il18bp

Sujet: The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.,IL18BP,IL18BPa,Immunology & Inflammation,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,IL18BP

Poids moléculaire: 12 kDa/17 kDa/21 kDa

ID gène: 10068

UniProt: O95998