IL21 Receptor anticorps (AA 20-240)
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- Antigène Voir toutes IL21 Receptor (IL21R) Anticorps
- IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
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Épitope
- AA 20-240
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IL21 Receptor est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- GVSMPRGWAA PLLLLLLQGG WGCPDLVCYT DYLQTVICIL EMWNLHPSTL TLTWQDQYEE LKDEATSCSL HRSAHNATHA TYTCHMDVFH FMADDIFSVN ITDQSGNYSQ ECGSFLLAES IKPAPPFNVT VTFSGQYNIS WRSDYEDPAF YMLKGKLQYE LQYRNRGDPW AVSPRRKLIS VDSRSVSLLP LEFRKDSSYE LQVRAGPMPG SSYQGTWSEW S
- Réactivité croisée
- Humain, Souris
- Attributs du produit
- Polyclonal Antibodies
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 20-240 of human IL21R (NP_851565.4).
- Isotype
- IgG
- Top Product
- Discover our top product IL21R Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000
- Commentaires
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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Berberine inhibits IL-21/IL-21R mediated inflammatory proliferation of fibroblast-like synoviocytes through the attenuation of PI3K/Akt signaling pathway and ameliorates IL-21 mediated ..." dans: Cytokine, Vol. 106, pp. 54-66, (2018) (PubMed).
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Berberine inhibits IL-21/IL-21R mediated inflammatory proliferation of fibroblast-like synoviocytes through the attenuation of PI3K/Akt signaling pathway and ameliorates IL-21 mediated ..." dans: Cytokine, Vol. 106, pp. 54-66, (2018) (PubMed).
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- Antigène
- IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
- Autre désignation
- IL21R (IL21R Produits)
- Synonymes
- anticorps IL21R, anticorps il-21ra.a, anticorps CD360, anticorps NILR, anticorps interleukin 21 receptor, anticorps interleukin 21 receptor, tandem duplicate 1, anticorps IL21R, anticorps il21r.1, anticorps Il21r
- Sujet
- The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.,IL21R,CD360,NILR,Immunology & Inflammation,CD markers,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,IL21R
- Poids moléculaire
- 59 kDa
- ID gène
- 50615
- UniProt
- Q9HBE5
- Pathways
- Signalistation JAK/STAT
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