INHBB anticorps (AA 293-407)

N° du produit ABIN6142461

Détail du produit anti-INHBB anticorps

Antigène: INHBB (Inhibin, beta B (INHBB))

Épitope: AA 293-407

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INHBB est non-conjugé

Application: Western Blotting (WB)

Séquence: GLECDGRTNL CCRQQFFIDF RLIGWNDWII APTGYYGNYC EGSCPAYLAG VPGSASSFHT AVVNQYRMRG LNPGTVNSCC IPTKLSTMSM LYFDDEYNIV KRDVPNMIVE ECGCA

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 293-407 of human INHBB (NP_002184.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur INHBB

Antigène: INHBB (Inhibin, beta B (INHBB))

Autre désignation: INHBB (INHBB Produits)

Synonymes: anticorps actbb, anticorps actbetaB, anticorps inhibin, anticorps inhibin, beta B, anticorps inhibin beta B L homeolog, anticorps inhibin beta B subunit, anticorps inhibin beta B, anticorps inhibin beta-B, anticorps inhibin beta B chain, anticorps inhbb, anticorps inhbb.L, anticorps INHBB, anticorps Inhbb, anticorps LOC100719829

Sujet: The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.,INHBB,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Immunology & Inflammation,Cytokines,Neuroscience,INHBB

Poids moléculaire: 45 kDa

ID gène: 3625

UniProt: P09529

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion