Importin 9 anticorps (AA 827-1041)
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- Antigène Voir toutes Importin 9 (IPO9) Anticorps
- Importin 9 (IPO9)
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Épitope
- AA 827-1041
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Importin 9 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Séquence
- LPGPTGKPAL EFVMAEWTSR QHLFYGQYEG KVSSVALCKL LQHGINADDK RLQDIRVKGE EIYSMDEGIR TRSKSAKNPE RWTNIPLLVK ILKLIINELS NVMEANAARQ ATPAEWSQDD SNDMWEDQEE EEEEEEDGLA GQLLSDILAT SKYEEDYYED DEEDDPDALK DPLYQIDLQA YLTDFLCQFA QQPCYIMFSG HLNDNERRVL QTIGI
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 827-1041 of human IPO9 (NP_060555.2).
- Isotype
- IgG
- Top Product
- Discover our top product IPO9 Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:100
- Commentaires
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- Importin 9 (IPO9)
- Autre désignation
- IPO9 (IPO9 Produits)
- Sujet
- Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates the nuclear import of RPS7, RPL18A, RPL6, histone H2A, histone H2B and histone. Prevents the cytoplasmic aggregation of RPS7 and RPL18A by shielding exposed basic domains. Mediates the nuclear import of actin (By similarity.,IPO9,Imp9,IPO9
- Poids moléculaire
- 115 kDa
- ID gène
- 55705
- UniProt
- Q96P70
- Pathways
- Protein targeting to Nucleus
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