IREB2 anticorps (AA 1-250)

N° du produit ABIN6142524

Détail du produit anti-IREB2 anticorps

Antigène: IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))

Épitope: AA 1-250

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IREB2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: MDAPKAGYAF EYLIETLNDS SHKKFFDVSK LGTKYDVLPY SIRVLLEAAV RNCDGFLMKK EDVMNILDWK TKQSNVEVPF FPARVLLQDF TGIPAMVDFA AMREAVKTLG GDPEKVHPAC PTDLTVDHSL QIDFSKCAIQ NAPNPGGGDL QKAGKLSPLK VQPKKLPCRG QTTCRGSCDS GELGRNSGTF SSQIENTPIL CPFHLQPVPE PETVLKNQEV EFGRNRERLQ FFKWSSRVFK NVAVIPPGTG

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human IREB2 (NP_004127.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:20 - 1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IREB2

Antigène: IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))

Autre désignation: IREB2 (IREB2 Produits)

Synonymes: anticorps IREB2, anticorps im:7153062, anticorps DKFZp468N047, anticorps D9Ertd85e, anticorps Irp2, anticorps ACO3, anticorps IRP2, anticorps IRP2AD, anticorps IREBP2, anticorps iron responsive element binding protein 2, anticorps iron-responsive element binding protein 2, anticorps iron responsive element binding protein 2 L homeolog, anticorps IREB2, anticorps ireb2, anticorps Ireb2, anticorps ireb2.L

Sujet: RNA-binding protein that binds to iron-responsive elements (IRES, which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.,IREB2,ACO3,IRP2,IRP2AD,Endocrine & Metabolism,Cardiovascular,Hypoxia,Hypoxia-Regulated,IREB2

Poids moléculaire: 37 kDa/105 kDa

ID gène: 3658

UniProt: P48200

Pathways: Transition Metal Ion Homeostasis