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IRF3 anticorps (AA 1-260)

Name: IRF3 anticorps (AA 1-260)
Brand: antibodies-online
SKU: ABIN6142528
Price: 722.37 EUR
Availability: InStock

IRF3 Reactivité: Humain WB, IHC, IF, ChIP Hôte: Lapin Polyclonal unconjugated

Western blot analysis of extracts of various cell lines, using IRF3 antibody. (IRF3 anticorps (AA 1-260))

Immunofluorescence analysis of HeLa cells using IRF3 antibody (ABIN6128099, ABIN6142528, ABIN6142531 and ABIN7101371) at dilution of 1:100 (40x lens). (IRF3 anticorps (AA 1-260))

Immunohistochemistry of paraffin-embedded human esophageal cancer using IRF3 antibody. (IRF3 anticorps (AA 1-260))

IHC (p)

Chromatin immunoprecipitation analysis extracts of HCT116 cell line, using IRF3 rabbit polyclonal antibody. (IRF3 anticorps (AA 1-260))

ChIP

Immunohistochemistry of paraffin-embedded human lung cancer using IRF3 antibody. (IRF3 anticorps (AA 1-260))

IHC (p)

5 images

(1 reference)

N° du produit ABIN6142528

Fiche de données

Antigène Voir toutes IRF3 Anticorps

IRF3 (Interferon Regulatory Factor 3 (IRF3))
Épitope
15

15

14

14

14

8

7

6

5

5

4

4

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-260
Reactivité
147

87

54

31

18

3

2

2

2

1

1

1

1
Humain
Hôte
146

20

2
Lapin
Anticorps secondaires appropriés
Clonalité
133

35
Polyclonal
Conjugué
92

11

8

7

4

4

4

4

4

4

2

2

2

2

2

2

2

2

2

2

2

2

2
Cet anticorp IRF3 est non-conjugé
Application
123

69

36

32

29

27

19

11

11

11

6

4

3

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)

Séquence

MGTPKPRILP WLVSQLDLGQ LEGVAWVNKS RTRFRIPWKH GLRQDAQQED FGIFQAWAEA TGAYVPGRDK PDLPTWKRNF RSALNRKEGL RLAEDRSKDP HDPHKIYEFV NSGVGDFSQP DTSPDTNGGG STSDTQEDIL DELLGNMVLA PLPDPGPPSL AVAPEPCPQP LRSPSLDNPT PFPNLGPSEN PLKRLLVPGE EWEFEVTAFY RGRQVFQQTI SCPEGLRLVG SEVGDRTLPG WPVTLPDPGM SLTDRGVMSY

Réactivité croisée

Humain, Souris, Rat

Attributs du produit

Polyclonal Antibodies

Immunogène

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human IRF3 (NP_001184051.1).

Isotype

IgG

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Indications d'application

WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,ChIP,1:20 - 1:100

Commentaires

HIGH QUALITY

Restrictions

For Research Use only
Format

Liquid

Buffer

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

-20 °C

Stockage commentaire

Store at -20°C. Avoid freeze / thaw cycles.
Zhong, Wang, Fang, Zhang, Luo, Shang, Ouyang, Ouyang, Chen, Xiao: "Ubiquitin-specific proteases 25 negatively regulates virus-induced type I interferon signaling." dans: PLoS ONE, Vol. 8, Issue 11, pp. e80976, (2013) (PubMed).
Antigène

IRF3 (Interferon Regulatory Factor 3 (IRF3))

Autre désignation

IRF3 (IRF3 Produits)

Synonymes

anticorps irf3, anticorps IRF3, anticorps C920001K05Rik, anticorps IRF-3, anticorps interferon regulatory factor 3, anticorps interferon regulatory factor 7, anticorps irf3, anticorps IRF3, anticorps irf-3, anticorps Irf3, anticorps IRF7

Sujet

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,IIAE7,IRF3,Epigenetics & Nuclear Signaling,Transcription Factors,Immunology & Inflammation,Cytokines,Interferons,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,IRF3

Poids moléculaire

12 kDa/16 kDa/33 kDa/47 kDa/49 kDa

ID gène

3661

UniProt

Q14653

Pathways

Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades