KIR3DS1 anticorps (AA 80-340)
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- Antigène Tous les produits KIR3DS1
- KIR3DS1 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Short Cytoplasmic Tail, 1 (KIR3DS1))
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Épitope
- AA 80-340
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KIR3DS1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- FNMSPVTTAH AGNYTCRGSH PHSPTGWSAP SNPMVIMVTG NHRKPSLLAH PGPLVKSGER VILQCWSDIM FEHFFLHKEW ISKDPSRLVG QIHDGVSKAN FSIGSMMRAL AGTYRCYGSV THTPYQLSAP SDPLDIVVTG LYEKPSLSAQ PGPKVQAGES VTLSCSSRSS YDMYHLSREG GAHERRLPAV RKVNRTFQAD FPLGPATHGG TYRCFGSFRH SPYEWSDPSD PLLVSVTGNP SSSWPSPTEP SSKSGNLRHL H
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 80-340 of human KIR3DS1 (NP_001077008.1).
- Isotype
- IgG
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- Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Commentaires
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- KIR3DS1 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Short Cytoplasmic Tail, 1 (KIR3DS1))
- Autre désignation
- KIR3DS1 (KIR3DS1 Produits)
- Synonymes
- anticorps CD158E2, anticorps KIR-123FM, anticorps KIR-G1, anticorps NKAT10, anticorps killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1, anticorps killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1, anticorps KIR3DS1
- Sujet
- Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,KIR3DS1,CD158E2,KIR-123FM,KIR-G1,NKAT-10,NKAT10,KIR3DS1
- Poids moléculaire
- 42 kDa
- ID gène
- 3813
- UniProt
- Q14943
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