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KPNB1 anticorps (AA 250-350)

KPNB1 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6142997
  • Antigène Voir toutes KPNB1 Anticorps
    KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))
    Épitope
    • 15
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 250-350
    Reactivité
    • 45
    • 18
    • 17
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 42
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 43
    • 3
    Polyclonal
    Conjugué
    • 22
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KPNB1 est non-conjugé
    Application
    • 34
    • 13
    • 13
    • 10
    • 10
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Séquence
    QYMETYMGPA LFAITIEAMK SDIDEVALQG IEFWSNVCDE EMDLAIEASE AAEQGRPPEH TSKFYAKGAL QYLVPILTQT LTKQDENDDD DDWNPCKAAG V
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    A synthetic peptide corresponding to a sequence within amino acids 250-350 of human KPNB1 (NP_002256.2).
    Isotype
    IgG
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))
    Autre désignation
    KPNB1 (KPNB1 Produits)
    Synonymes
    anticorps Afu1g15720, anticorps AO090005001133, anticorps imb1, anticorps impnb, anticorps ipo1, anticorps ipob, anticorps ntf97, anticorps IMB1, anticorps IPO1, anticorps IPOB, anticorps Impnb, anticorps NTF97, anticorps AA409963, anticorps importin beta-1 subunit, anticorps Importin beta-1 subunit, anticorps karyopherin (importin) beta 1 L homeolog, anticorps importin beta 1, anticorps karyopherin subunit beta 1, anticorps karyopherin (importin) beta 1, anticorps AFUA_1G15720, anticorps AOR_1_1974174, anticorps Bm1_57540, anticorps PMAA_065830, anticorps AFLA_083750, anticorps TSTA_085870, anticorps BDBG_07509, anticorps MCYG_00039, anticorps kpnb1.L, anticorps LOC100533387, anticorps KPNB1, anticorps Kpnb1
    Sujet
    Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. Two transcript variants encoding different isoforms have been found for this gene.,KPNB1,IMB1,IPO1,IPOB,Impnb,NTF97,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Lipid Metabolism,Immunology & Inflammation,KPNB1
    Poids moléculaire
    81 kDa/97 kDa
    ID gène
    3837
    UniProt
    Q14974
    Pathways
    Protein targeting to Nucleus
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