MBNL1 anticorps (AA 1-382)

N° du produit ABIN6143601

Détail du produit anti-MBNL1 anticorps

Antigène: MBNL1 (Muscleblind-like Protein 1 (MBNL1))

Épitope: AA 1-382

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBNL1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: MAVSVTPIRD TKWLTLEVCR EFQRGTCSRP DTECKFAHPS KSCQVENGRV IACFDSLKGR CSRENCKYLH PPPHLKTQLE INGRNNLIQQ KNMAMLAQQM QLANAMMPGA PLQPVPMFSV APSLATNASA AAFNPYLGPV SPSLVPAEIL PTAPMLVTGN PGVPVPAAAA AAAQKLMRTD RLEVCREYQR GNCNRGENDC RFAHPADSTM IDTNDNTVTV CMDYIKGRCS REKCKYFHPP AHLQAKIKAA QYQVNQAAAA QAAATAAAMG IPQAVLPPLP KRPALEKTNG ATAVFNTGIF QYQQALANMQ LQQHTAFLPP GSILCMTPAT SVVPMVHGAT PATVSAATTS ATSVPFAATA TANQIPIISA EHLTSHKYVT QM

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-382 of human MBNL1 (NP_066368.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MBNL1

Antigène: MBNL1 (Muscleblind-like Protein 1 (MBNL1))

Autre désignation: MBNL1 (MBNL1 Produits)

Synonymes: anticorps MBNL1, anticorps zgc:153954, anticorps Mbnl, anticorps mKIAA0428, anticorps EXP, anticorps EXP35, anticorps EXP40, anticorps EXP42, anticorps MBNL, anticorps muscleblind like splicing regulator 1, anticorps muscleblind-like splicing regulator 1, anticorps muscleblind like splicing factor 1, anticorps MBNL1, anticorps mbnl1, anticorps Mbnl1

Sujet: This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities.,MBNL1,EXP,MBNL,Epigenetics & Nuclear Signaling,RNA Binding,MBNL1

Poids moléculaire: 33 kDa/34 kDa/36 kDa/37 kDa/39 kDa/40 kDa/41 kDa

ID gène: 4154

UniProt: Q9NR56

Pathways: Ribonucleoprotein Complex Subunit Organization