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MCFD2 anticorps (AA 27-146)

MCFD2 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6143636
  • Antigène Voir toutes MCFD2 Anticorps
    MCFD2 (Multiple Coagulation Factor Deficiency 2 (MCFD2))
    Épitope
    • 15
    • 7
    • 2
    • 1
    AA 27-146
    Reactivité
    • 25
    • 23
    • 22
    Humain
    Hôte
    • 29
    • 11
    Lapin
    Clonalité
    • 30
    • 10
    Polyclonal
    Conjugué
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MCFD2 est non-conjugé
    Application
    • 27
    • 15
    • 13
    • 13
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    EEPAASFSQP GSMGLDKNTV HDQEHIMEHL EGVINKPEAE MSPQELQLHY FKMHDYDGNN LLDGLELSTA ITHVHKEEGS EQAPLMSEDE LINIIDGVLR DDDKNNDGYI DYAEFAKSLQ
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 27-146 of human MCFD2 (NP_644808.1).
    Isotype
    IgG
    Top Product
    Discover our top product MCFD2 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:100 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    MCFD2 (Multiple Coagulation Factor Deficiency 2 (MCFD2))
    Autre désignation
    MCFD2 (MCFD2 Produits)
    Synonymes
    anticorps hm:zeh1186, anticorps wu:fc23b10, anticorps wu:fd50d08, anticorps zgc:103713, anticorps zgc:109915, anticorps MCFD2, anticorps DKFZp469B098, anticorps F5F8D, anticorps F5F8D2, anticorps LMAN1IP, anticorps SDNSF, anticorps 1810021C21Rik, anticorps F5f8d, anticorps Lman1ip, anticorps Sdnsf, anticorps multiple coagulation factor deficiency 2, anticorps multiple coagulation factor deficiency 2 L homeolog, anticorps MCFD2, anticorps mcfd2, anticorps mcfd2.L, anticorps Mcfd2
    Sujet
    This gene encodes a soluble luminal protein with two calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LMAN1 (lectin mannose binding protein 1, also known as ERGIC-53) that facilitates the transport of coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment (ERGIC). Mutations in this gene cause combined deficiency of FV and FVIII (F5F8D), a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular germ cell tumors. The 3' UTR of this gene contains a transposon-like human repeat element named 'THE 1'. A processed RNA pseudogene of this gene is on chromosome 6p22.1. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,MCFD2,F5F8D,F5F8D2,LMAN1IP,SDNSF,Signal Transduction,MCFD2
    Poids moléculaire
    10 kDa/14 kDa/16 kDa
    ID gène
    90411
    UniProt
    Q8NI22
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