MCFD2 anticorps (AA 27-146)

N° du produit ABIN6143636

Détail du produit anti-MCFD2 anticorps

Antigène: MCFD2 (Multiple Coagulation Factor Deficiency 2 (MCFD2))

Épitope: AA 27-146

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCFD2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: EEPAASFSQP GSMGLDKNTV HDQEHIMEHL EGVINKPEAE MSPQELQLHY FKMHDYDGNN LLDGLELSTA ITHVHKEEGS EQAPLMSEDE LINIIDGVLR DDDKNNDGYI DYAEFAKSLQ

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 27-146 of human MCFD2 (NP_644808.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MCFD2

Antigène: MCFD2 (Multiple Coagulation Factor Deficiency 2 (MCFD2))

Autre désignation: MCFD2 (MCFD2 Produits)

Synonymes: anticorps hm:zeh1186, anticorps wu:fc23b10, anticorps wu:fd50d08, anticorps zgc:103713, anticorps zgc:109915, anticorps MCFD2, anticorps DKFZp469B098, anticorps F5F8D, anticorps F5F8D2, anticorps LMAN1IP, anticorps SDNSF, anticorps 1810021C21Rik, anticorps F5f8d, anticorps Lman1ip, anticorps Sdnsf, anticorps multiple coagulation factor deficiency 2, anticorps multiple coagulation factor deficiency 2 L homeolog, anticorps MCFD2, anticorps mcfd2, anticorps mcfd2.L, anticorps Mcfd2

Sujet: This gene encodes a soluble luminal protein with two calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LMAN1 (lectin mannose binding protein 1, also known as ERGIC-53) that facilitates the transport of coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment (ERGIC). Mutations in this gene cause combined deficiency of FV and FVIII (F5F8D), a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular germ cell tumors. The 3' UTR of this gene contains a transposon-like human repeat element named 'THE 1'. A processed RNA pseudogene of this gene is on chromosome 6p22.1. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,MCFD2,F5F8D,F5F8D2,LMAN1IP,SDNSF,Signal Transduction,MCFD2

Poids moléculaire: 10 kDa/14 kDa/16 kDa

ID gène: 90411

UniProt: Q8NI22