MCM10 anticorps (AA 616-875)

N° du produit ABIN6143639

Détail du produit anti-MCM10 anticorps

Antigène: MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

Épitope: AA 616-875

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM10 est non-conjugé

Application: Western Blotting (WB)

Séquence: RLEGAPATMT PKLGRGVLEG DDVLFYDESP PPRPKLSALA EAKKLAAITK LRAKGQVLTK TNPNSIKKKQ KDPQDILEVK ERVEKNTMFS SQAEDELEPA RKKRREQLAY LESEEFQKIL KAKSKHTGIL KEAEAEMQER YFEPLVKKEQ MEEKMRNIRE VKCRVVTCKT CAYTHFKLLE TCVSEQHEYH WHDGVKRFFK CPCGNRSISL DRLPNKHCSN CGLYKWERDG MLKEKTGPKI GGETLLPRGE EHAKFLNSLK

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 616-875 of human MCM10 (NP_877428.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MCM10

Antigène: MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

Autre désignation: MCM10 (MCM10 Produits)

Synonymes: anticorps CG9241, anticorps DmMCM10, anticorps Dmel\\CG9241, anticorps Scim19, anticorps mcm10, anticorps CNA43, anticorps DNA43, anticorps xmcm10, anticorps 2410041F14Rik, anticorps AU018508, anticorps C330019M07Rik, anticorps C79164, anticorps Minichromosome maintenance 10, anticorps minichromosome maintenance 10 replication initiation factor, anticorps minichromosome maintenance 10 replication initiation factor L homeolog, anticorps Mcm10, anticorps MCM10, anticorps mcm10.L

Sujet: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified.,MCM10,CNA43,DNA43,PRO2249,Epigenetics & Nuclear Signaling,MCM10

Poids moléculaire: 98 kDa

ID gène: 55388

UniProt: Q7L590

Pathways: Mitotic G1-G1/S Phases, DNA Replication