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MDC1 anticorps (AA 1-100)

Name: MDC1 anticorps (AA 1-100)
Brand: antibodies-online
SKU: ABIN6143659
Price: 722.37 EUR
Availability: InStock

MDC1 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated

Immunohistochemistry of paraffin-embedded human esophageal cancer using MDC1 Rabbit pAb (ABIN6134688, ABIN6143659, ABIN6143661 and ABIN6216452) at dilution of 1:150 (40x lens). (MDC1 anticorps (AA 1-100))

IHC

Immunofluorescence analysis of U-2 OS cells using MDC1 Rabbit pAb (ABIN6134688, ABIN6143659, ABIN6143661 and ABIN6216452) at dilution of 1:150 (40x lens). (MDC1 anticorps (AA 1-100))

Western blot analysis of extracts of mouse testis, using MDC1 antibody (ABIN6134688, ABIN6143659, ABIN6143661 and ABIN6216452) at 1:3000 dilution. (MDC1 anticorps (AA 1-100))

Immunohistochemistry of paraffin-embedded mouse testis using MDC1 Rabbit pAb (ABIN6134688, ABIN6143659, ABIN6143661 and ABIN6216452) at dilution of 1:150 (40x lens). (MDC1 anticorps (AA 1-100))

IHC

4 images

N° du produit ABIN6143659

Fiche de données

Antigène Voir toutes MDC1 Anticorps

MDC1 (Mdc1 (MDC1))
Épitope
22

17

15

10

5

3

2

2

2

1

1

1

1

1

1

1

1
AA 1-100
Reactivité
59

54

16

12

11

2

1

1
Humain
Hôte
49

37
Lapin
Anticorps secondaires appropriés
Clonalité
49

37
Polyclonal
Conjugué
29

6

6

4

3

3

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp MDC1 est non-conjugé
Application
66

30

14

13

13

13

11

10

9

6

3

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence

MEDTQAIDWD VEEEEETEQS SESLRCNVEP VGRLHIFSGA HGPEKDFPLH LGKNVVGRMP DCSVALPFPS ISKQHAEIEI LAWDKAPILR DCGSLNGTQI

Réactivité croisée

Humain, Souris

Attributs du produit

Polyclonal Antibodies

Immunogène

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MDC1 (NP_055456.2).

Isotype

IgG

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anti-Mdc1 (MDC1) (N-Term) antibody
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anti-Mdc1 (MDC1) (N-Term) antibody (FITC)
MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 FITC

anti-Mdc1 (MDC1) (N-Term) antibody (Alkaline Phosphatase (AP))
MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 Alkaline Phosphatase (AP)

anti-Mdc1 (MDC1) (N-Term) antibody (Biotin)
MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 Biotin

anti-Mdc1 (MDC1) (N-Term) antibody (PE)
MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 PE

anti-Mdc1 (MDC1) (N-Term) antibody (APC)
MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 APC

anti-Mdc1 (MDC1) (N-Term) antibody (PerCP)
MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 PerCP

Indications d'application

WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions

For Research Use only
Format

Liquid

Buffer

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

-20 °C

Stockage commentaire

Store at -20°C. Avoid freeze / thaw cycles.
Antigène

MDC1 (Mdc1 (MDC1))

Autre désignation

MDC1 (MDC1 Produits)

Synonymes

anticorps 6820401C03, anticorps AA413496, anticorps Nfbd1, anticorps mKIAA0170, anticorps NFBD1, anticorps mediator of DNA damage checkpoint 1, anticorps mediator of DNA-damage checkpoint 1, anticorps Mdc1, anticorps MDC1

Sujet

The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.,MDC1,NFBD1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,MDC1

Poids moléculaire

116 kDa/195 kDa/197 kDa/226 kDa

ID gène

9656

UniProt

Q14676