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MDC1 anticorps (AA 1-350)

MDC1 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6143660
  • Antigène Voir toutes MDC1 Anticorps
    MDC1 (Mdc1 (MDC1))
    Épitope
    • 22
    • 17
    • 15
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-350
    Reactivité
    • 59
    • 54
    • 16
    • 12
    • 11
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 49
    • 37
    Lapin
    Clonalité
    • 49
    • 37
    Polyclonal
    Conjugué
    • 29
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MDC1 est non-conjugé
    Application
    • 66
    • 30
    • 14
    • 13
    • 13
    • 13
    • 11
    • 10
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Séquence
    MEDTQAIDWD VEEEEETEQS SESLRCNVEP VGRLHIFSGA HGPEKDFPLH LGKNVVGRMP DCSVALPFPS ISKQHAEIEI LAWDKAPILR DCGSLNGTQI LRPPKVLSPG VSHRLRDQEL ILFADLLCQY HRLDVSLPFV SRGPLTVEET PRVQGETQPQ RLLLAEDSEE EVDFLSERRM VKKSRTTSSS VIVPESDEEG HSPVLGGLGP PFAFNLNSDT DVEEGQQPAT EEASSAARRG ATVEAKQSEA EVVTEIQLEK DQPLVKERDN DTKVKRGAGN GVVPAGVILE RSQPPGEDSD TDVDDDSRPP GRPAEVHLER AQPFGFIDSD TDAEEERIPA TPVVIPMKKR
     Réactivité croisée
    Humain
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human MDC1 (NP_055456.2).
    Isotype
    IgG
    Top Product
    Discover our top product MDC1 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    MDC1 (Mdc1 (MDC1))
    Autre désignation
    MDC1 (MDC1 Produits)
    Synonymes
    anticorps 6820401C03, anticorps AA413496, anticorps Nfbd1, anticorps mKIAA0170, anticorps NFBD1, anticorps mediator of DNA damage checkpoint 1, anticorps mediator of DNA-damage checkpoint 1, anticorps Mdc1, anticorps MDC1
    Sujet
    The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.,MDC1,NFBD1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,MDC1
    Poids moléculaire
    116 kDa/195 kDa/197 kDa/226 kDa
    ID gène
    9656
    UniProt
    Q14676
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