MDC1 anticorps (AA 1-350)
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- Antigène Voir toutes MDC1 Anticorps
- MDC1 (Mdc1 (MDC1))
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Épitope
- AA 1-350
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MDC1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Séquence
- MEDTQAIDWD VEEEEETEQS SESLRCNVEP VGRLHIFSGA HGPEKDFPLH LGKNVVGRMP DCSVALPFPS ISKQHAEIEI LAWDKAPILR DCGSLNGTQI LRPPKVLSPG VSHRLRDQEL ILFADLLCQY HRLDVSLPFV SRGPLTVEET PRVQGETQPQ RLLLAEDSEE EVDFLSERRM VKKSRTTSSS VIVPESDEEG HSPVLGGLGP PFAFNLNSDT DVEEGQQPAT EEASSAARRG ATVEAKQSEA EVVTEIQLEK DQPLVKERDN DTKVKRGAGN GVVPAGVILE RSQPPGEDSD TDVDDDSRPP GRPAEVHLER AQPFGFIDSD TDAEEERIPA TPVVIPMKKR
- Réactivité croisée
- Humain
- Attributs du produit
- Polyclonal Antibodies
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human MDC1 (NP_055456.2).
- Isotype
- IgG
- Top Product
- Discover our top product MDC1 Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- MDC1 (Mdc1 (MDC1))
- Autre désignation
- MDC1 (MDC1 Produits)
- Synonymes
- anticorps 6820401C03, anticorps AA413496, anticorps Nfbd1, anticorps mKIAA0170, anticorps NFBD1, anticorps mediator of DNA damage checkpoint 1, anticorps mediator of DNA-damage checkpoint 1, anticorps Mdc1, anticorps MDC1
- Sujet
- The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.,MDC1,NFBD1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,MDC1
- Poids moléculaire
- 116 kDa/195 kDa/197 kDa/226 kDa
- ID gène
- 9656
- UniProt
- Q14676
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