MLH3 anticorps (AA 1180-1429)

N° du produit ABIN6143878

Détail du produit anti-MLH3 anticorps

Antigène: MLH3 (MutL Homolog 3 (MLH3))

Épitope: AA 1180-1429

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLH3 est non-conjugé

Application: Western Blotting (WB)

Séquence: RFTKGMIHSM QVLQQVDNKF IACLMSTKTE ENGEADSYEK QQAQGSGRKK LLSSTLIPPL EITVTEEQRR LLWCYHKNLE DLGLEFVFPD TSDSLVLVGK VPLCFVEREA NELRRGRSTV TKSIVEEFIR EQLELLQTTG GIQGTLPLTV QKVLASQACH GAIKFNDGLS LQESCRLIEA LSSCQLPFQC AHGRPSMLPL ADIDHLEQEK QIKPNLTKLR KMAQAWRLFG KAECDTRQSL QQSMPPCEPP

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1180-1429 of human MLH3 (NP_055196.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MLH3

Antigène: MLH3 (MutL Homolog 3 (MLH3))

Autre désignation: MLH3 (MLH3 Produits)

Synonymes: anticorps AV125803, anticorps BB126472, anticorps MGC80774, anticorps MLH3, anticorps HNPCC7, anticorps mutL homolog 3, anticorps mutL homolog 3 L homeolog, anticorps Mlh3, anticorps mlh3.L, anticorps MLH3, anticorps mlh3

Sujet: This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.,MLH3,HNPCC7,Epigenetics & Nuclear Signaling,DNA Damage & Repair,MLH3

Poids moléculaire: 161 kDa/163 kDa

ID gène: 27030

UniProt: Q9UHC1

Pathways: Chromatin Binding