MSL2 anticorps (AA 328-577)

N° du produit ABIN6144069

Détail du produit anti-MSL2 anticorps

Antigène: MSL2 (Male-Specific Lethal 2 Homolog (MSL2))

Épitope: AA 328-577

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MSL2 est non-conjugé

Application: Western Blotting (WB)

Séquence: CTAATPKIAK LNRKRSRSES DSEKVQPLPI STIIRGPTLG ASAPVTVKRE SKISLQPIAT VPNGGTTPKI SKTVLLSTKS MKKSHEHGSK KSHSKTKPGI LKKDKAVKEK IPSHHFMPGS PTKTVYKKPQ EKKGCKCGRA TQNPSVLTCR GQRCPCYSNR KACLDCICRG CQNSYMANGE KKLEAFAVPE KALEQTRLTL GINVTSIAVR NASTSTSVIN VTGSPVTTFL AASTHDDKSL DEAIDMRFDC

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 328-577 of human MSL2 (NP_060603.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MSL2

Antigène: MSL2 (Male-Specific Lethal 2 Homolog (MSL2))

Autre désignation: MSL2 (MSL2 Produits)

Synonymes: anticorps MSL-2, anticorps MSL2L1, anticorps RNF184, anticorps E130103E02Rik, anticorps Msl2l1, anticorps Rnf184, anticorps RGD1310355, anticorps MSL complex subunit 2, anticorps male-specific lethal 2 homolog (Drosophila), anticorps MSL2, anticorps Msl2

Sujet: Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub, but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me and 'Lys-79' (H3K79me and leads to gene activation, including that of HOXA9 and MEIS1.,MSL2,MSL-2,MSL2L1,RNF184,Epigenetics & Nuclear Signaling,MSL2

Poids moléculaire: 54 kDa/62 kDa

ID gène: 55167

UniProt: Q9HCI7