N4BP1 anticorps (AA 190-590)

N° du produit ABIN6144311

Détail du produit anti-N4BP1 anticorps

Antigène: N4BP1 (NEDD4 Binding Protein 1 (N4BP1))

Épitope: AA 190-590

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp N4BP1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: TQGEESLFET DDDVITVGDV RPPEYTQSAA TGPSSARDEV VVQEDSRNKA RTPVSELTKH MDTVFSSSPD VLFVPVNGLS PDEDALSKDR VCHKRRSSDT EERHTKKQFS LENVPEGELL PDGKGSAGNE VIDLSDPASN STNLSPDGKD TTEEMEYNIL VNFFKTMGYS QEIVEKVIRE YGPSTEPLLL LEEIEKENKR LQEDRDFPPC TVYPDASQSR NAGVGSTTNE LTADSTPKKA QSHTEQSMVE RFSQLPFKDS KHCTSNCKVN SFRTVPVGQK QEIWGSKQNS SCTVDLETDG HSASAASASP KDISFVSRGA SGHQQRNPAF PENGFQQQTE PLLPNNTKPA CEKRSGSCSS PQPKPNYPPL SPPLPLPQLL PSVTEARLGG SSDHIDSSVT G

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 190-590 of mouse N4BP1 (NP_085040.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur N4BP1

Antigène: N4BP1 (NEDD4 Binding Protein 1 (N4BP1))

Autre désignation: N4BP1 (N4BP1 Produits)

Synonymes: anticorps AI481586, anticorps C81621, anticorps RGD1305179, anticorps wu:fi03b05, anticorps zgc:66437, anticorps NEDD4 binding protein 1, anticorps Nedd4 binding protein 1, anticorps nedd4 binding protein 1, anticorps nedd4 binding protein 1 L homeolog, anticorps N4BP1, anticorps N4bp1, anticorps n4bp1, anticorps n4bp1.L

Sujet: Potent suppressor of cytokine production that acts as a regulator of innate immune signaling and inflammation. Acts as a key negative regulator of select cytokine and chemokine responses elicited by TRIF-independent Toll-like receptors (TLRs, thereby limiting inflammatory cytokine responses to minor insults. In response to more threatening pathogens, cleaved by CASP8 downstream of TLR3 or TLR4, leading to its inactivation, thereby allowing production of inflammatory cytokines (By similarity. Acts as a restriction factor against some viruses, such as HIV-1: restricts HIV-1 replication by binding to HIV-1 mRNAs and mediating their degradation via its ribonuclease activity. Also acts as an inhibitor of the E3 ubiquitin-protein ligase ITCH: acts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates (By similarity.,N4BP1,Epigenetics & Nuclear Signaling,N4BP1

Poids moléculaire: 99 kDa

ID gène: 80750

UniProt: O75113