NCOR2 anticorps (AA 670-900)
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- Antigène Voir toutes NCOR2 Anticorps
- NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))
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Épitope
- AA 670-900
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NCOR2 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Séquence
- KLKMEKERNA RRKKKKAPAA ASEEAAFPPV VEDEEMEASG VSGNEEEMVE EAEALHASGN EVPRGECSGP ATVNNSSDTE SIPSPHTEAA KDTGQNGPKP PATLGADGPP PGPPTPPPED IPAPTEPTPA SEATGAPTPP PAPPSPSAPP PVVPKEEKEE ETAAAPPVEE GEEQKPPAAE ELAVDTGKAE EPVKSECTEE AEEGPAKGKD AEAAEATAEG ALKAEKKEGG S
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 670-900 of human NCOR2 (NP_006303.4).
- Isotype
- IgG
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- Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100
- Commentaires
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))
- Autre désignation
- NCOR2 (NCOR2 Produits)
- Sujet
- This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.,NCOR2,CTG26,N-CoR2,SMAP270,SMRT,SMRTE,SMRTE-tau,TNRC14,TRAC,TRAC-1,TRAC1,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Notch Signaling Pathway,Endocrine & Metabolism,Lipid Metabolism,NCOR2
- Poids moléculaire
- 81 kDa/268 kDa/273 kDa/274 kDa
- ID gène
- 9612
- UniProt
- Q9Y618
- Pathways
- Signalisation Notch, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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