NR1I3 anticorps (AA 103-352)
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- Antigène Voir toutes NR1I3 Anticorps
- NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
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Épitope
- AA 103-352
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NR1I3 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Séquence
- PVQLSKEQEE LIRTLLGAHT RHMGTMFEQF VQFRPPAHLF IHHQPLPTLA PVLPLVTHFA DINTFMVLQV IKFTKDLPVF RSLPIEDQIS LLKGAAVEIC HIVLNTTFCL QTQNFLCGPL RYTIEDGARV SPTVGFQVEF LELLFHFHGT LRKLQLQEPE YVLLAAMALF SPDRPGVTQR DEIDQLQEEM ALTLQSYIKG QQRRPRDRFL YAKLLGLLAE LRSINEAYGY QIQHIQGLSA MMPLLQEICS
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 103-352 of human NR1I3 (NP_001070948.1).
- Isotype
- IgG
- Top Product
- Discover our top product NR1I3 Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Commentaires
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
- Autre désignation
- NR1I3 (NR1I3 Produits)
- Synonymes
- anticorps AA209988, anticorps AI551208, anticorps CAR, anticorps CAR-beta, anticorps Care2, anticorps ESTM32, anticorps MB67, anticorps CAR1, anticorps CXR, anticorps nuclear receptor subfamily 1 group I member 3, anticorps nuclear receptor subfamily 1, group I, member 3, anticorps NR1I3, anticorps Nr1i3
- Sujet
- This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene.,NR1I3,CAR,CAR1,NR1I3,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Drug metabolism,NR1I3
- Poids moléculaire
- 30-40 kDa
- ID gène
- 9970
- UniProt
- Q14994
- Pathways
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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