NRARP anticorps (AA 1-114)

N° du produit ABIN6144838

Détail du produit anti-NRARP anticorps

Antigène: NRARP (NOTCH-Regulated Ankyrin Repeat Protein (NRARP))

Épitope: AA 1-114

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NRARP est non-conjugé

Application: Western Blotting (WB)

Séquence: MSQAELSTCS APQTQRIFQE AVRKGNTQEL QSLLQNMTNC EFNVNSFGPE GQTALHQSVI DGNLELVKLL VKFGADIRLA NRDGWSALHI AAFGGHQDIV LYLITKAKYA ASGR

Réactivité croisée: Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-114 of human NRARP (NP_001004354.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NRARP

Antigène: NRARP (NOTCH-Regulated Ankyrin Repeat Protein (NRARP))

Autre désignation: NRARP (NRARP Produits)

Synonymes: anticorps 2700054M22Rik, anticorps Nrarp-a, anticorps fc89b12, anticorps id:ibd2282, anticorps wu:fa14d10, anticorps wu:fc89b12, anticorps zgc:100826, anticorps Nrarp-b, anticorps zgc:101875, anticorps Notch-regulated ankyrin repeat protein, anticorps NOTCH regulated ankyrin repeat protein, anticorps NOTCH regulated ankyrin repeat protein S homeolog, anticorps NOTCH-regulated ankyrin repeat protein, anticorps NOTCH regulated ankyrin repeat protein a, anticorps NOTCH regulated ankyrin repeat protein b, anticorps Nrarp, anticorps NRARP, anticorps nrarp.S, anticorps nrarpa, anticorps nrarpb

Sujet: Downstream effector of Notch signaling. Involved in the regulation of liver cancer cells self-renewal. Involved in angiogenesis acting downstream of Notch at branch points to regulate vascular density. Proposed to integrate endothelial Notch and Wnt signaling to control stalk cell proliferation and to stablilize new endothelial connections during angiogenesis. During somitogenesis involved in maintenance of proper somite segmentation and proper numbers of somites and vertebrae. Required for proper anterior-posterior somite patterning. Proposed to function in a negative feedback loop to destabilize Notch 1 intracellular domain (NICD and downregulate the Notch signal, preventing expansion of the Notch signal into the anterior somite domain (By similarity.,NRARP,Cell Biology & Developmental Biology,Neuroscience,Cardiovascular,Angiogenesis,NRARP

Poids moléculaire: 12 kDa

ID gène: 441478

UniProt: Q7Z6K4