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Occludin anticorps (AA 263-522)

Name: Occludin anticorps (AA 263-522)
Brand: antibodies-online
SKU: ABIN6144996
Price: 722.37 EUR
Availability: InStock

OCLN Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated

TMP has a protective effect on the LPS-induced BBB destruction in sepsis. (Occludin anticorps (AA 263-522))

Western blot analysis of extracts of various cell lines, using OCLN antibody. (Occludin anticorps (AA 263-522))

Immunofluorescence analysis of HeLa cells using OCLN antibody. (Occludin anticorps (AA 263-522))

Immunofluorescence analysis of NIH/3T3 cells using OCLN antibody. (Occludin anticorps (AA 263-522))

Immunohistochemistry of paraffin-embedded mouse ovary using OCLN antibody. (Occludin anticorps (AA 263-522))

Pinocembrin increased the expression of tight junction proteins in vitro(A) Caco-2 cells were treated with different concentration of pinocembrin (0-150 μM) for 24 h, and then the mRNA expression of Occludin, Claudin-1 and JAM-A in Caco-2 cells were determined by qRT-PCR. (Occludin anticorps (AA 263-522))

12 images

(1 reference)

N° du produit ABIN6144996

Fiche de données

Antigène Voir toutes Occludin (OCLN) Anticorps

Occludin (OCLN)
Épitope
16

16

15

9

7

6

5

4

3

3

2

2

2

2

1

1

1

1

1

1

1
AA 263-522
Reactivité
103

66

47

34

18

13

3

3

3

2

2

2
Humain
Hôte
86

18

3

1
Lapin
Anticorps secondaires appropriés
Clonalité
85

23
Polyclonal
Conjugué
45

9

7

6

4

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2
Cet anticorp Occludin est non-conjugé
Application
86

34

28

26

26

15

14

13

11

7

6

2

2

1

1
Western Blotting (WB)

Séquence

FAVKTRRKMD RYDKSNILWD KEHIYDEQPP NVEEWVKNVS AGTQDVPSPP SDYVERVDSP MAYSSNGKVN DKRFYPESSY KSTPVPEVVQ ELPLTSPVDD FRQPRYSSGG NFETPSKRAP AKGRAGRSKR TEQDHYETDY TTGGESCDEL EEDWIREYPP ITSDQQRQLY KRNFDTGLQE YKSLQSELDE INKELSRLDK ELDDYREESE EYMAAADEYN RLKQVKGSAD YKSKKNHCKQ LKSKLSHIKK MVGDYDRQKT

Réactivité croisée

Humain, Souris, Rat

Attributs du produit

Polyclonal Antibodies

Immunogène

Recombinant fusion protein containing a sequence corresponding to amino acids 263-522 of human Occludin (NP_002529.1).

Isotype

IgG

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Indications d'application

WB,1:1000 - 1:2000

Commentaires

HIGH QUALITY

Restrictions

For Research Use only
Format

Liquid

Buffer

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

-20 °C

Stockage commentaire

Store at -20°C. Avoid freeze / thaw cycles.
Knowlton, Fernández de Castro, Ashbrook, Gestaut, Zamora, Bauer, Forrest, Frydman, Risco, Dermody: "The TRiC chaperonin controls reovirus replication through outer-capsid folding." dans: Nature microbiology, Vol. 3, Issue 4, pp. 481-493, (2018) (PubMed).
Antigène

Occludin (OCLN)

Autre désignation

OCLN (OCLN Produits)

Synonymes

anticorps AI503564, anticorps Ocl, anticorps ocln, anticorps oclnb, anticorps tpmt, anticorps OCLN, anticorps wu:fd23h10, anticorps wu:fi13c01, anticorps zgc:113992, anticorps zgc:56359, anticorps BLCPMG, anticorps occludin, anticorps occludin S homeolog, anticorps occludin a, anticorps Ocln, anticorps OCLN, anticorps ocln.S, anticorps ocln, anticorps oclna

Sujet

This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.,OCLN,BLCPMG,PPP1R115,PTORCH1,occludin,Occludin,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Adhesion,Tight Junctions,Cytoskeleton,OCLN

Poids moléculaire

8 kDa/23 kDa/31 kDa/52 kDa/54 kDa/59 kDa

ID gène

100506658

UniProt

Q16625

Pathways

Cell-Cell Junction Organization, Hepatitis C