OPA1 anticorps (AA 661-960)

N° du produit ABIN6145031

Détail du produit anti-OPA1 anticorps

Antigène: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Épitope: AA 661-960

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OPA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: TDKQLPNKAV EVAWETLQEE FSRFMTEPKG KEHDDIFDKL KEAVKEESIK RHKWNDFAED SLRVIQHNAL EDRSISDKQQ WDAAIYFMEE ALQARLKDTE NAIENMVGPD WKKRWLYWKN RTQEQCVHNE TKNELEKMLK CNEEHPAYLA SDEITTVRKN LESRGVEVDP SLIKDTWHQV YRRHFLKTAL NHCNLCRRGF YYYQRHFVDS ELECNDVVLF WRIQRMLAIT ANTLRQQLTN TEVRRLEKNV KEVLEDFAED GEKKIKLLTG KRVQLAEDLK KVREIQEKLD AFIEALHQEK

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 661-960 of human OPA1 (NP_056375.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-OPA1 (ABIN6145031)

Shao, Zhao, Wang, Liu, Zong, Xing: "Copper-Mediated Mitochondrial Fission/Fusion Is Associated with Intrinsic Apoptosis and Autophagy in the Testis Tissues of Chicken." dans: Biological trace element research, (2018) (PubMed).

Détails sur OPA1

Antigène: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Autre désignation: OPA1 (OPA1 Produits)

Synonymes: anticorps 1200011N24Rik, anticorps AI225888, anticorps AI847218, anticorps lilr3, anticorps mKIAA0567, anticorps MGM1, anticorps NPG, anticorps NTG, anticorps largeG, anticorps fk62d06, anticorps wu:fb77a10, anticorps wu:fk62d06, anticorps zgc:92092, anticorps OPA1, mitochondrial dynamin like GTPase, anticorps optic atrophy 1 (autosomal dominant), anticorps Opa1, anticorps OPA1, anticorps opa1

Sujet: This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.,OPA1,BERHS,MGM1,MTDPS14,NPG,NTG,largeG,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitophagy fission and fusion,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Heart,Cardiac metabolism,OPA1

Poids moléculaire: 111 kDa/115 kDa

ID gène: 4976

UniProt: O60313

Pathways: Tube Formation