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PABPN1 anticorps (AA 1-100)

PABPN1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6145153
  • Antigène Voir toutes PABPN1 Anticorps
    PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))
    Épitope
    • 8
    • 8
    • 6
    • 2
    • 2
    • 2
    AA 1-100
    Reactivité
    • 39
    • 20
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    Humain
    Hôte
    • 39
    Lapin
    Clonalité
    • 30
    • 9
    Polyclonal
    Conjugué
    • 15
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp PABPN1 est non-conjugé
    Application
    • 24
    • 13
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    MAAAAAAAAA AGAAGGRGSG PGRRRHLVPG AGGEAGEGAP GGAGDYGNGL ESEELEPEEL LLEPEPEPEP EEEPPRPRAP PGAPGPGPGS GAPGSQEEEE
     Réactivité croisée
    Humain, Souris
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PABPN1 (NP_004634.1).
    Isotype
    IgG
    Top Product
    Discover our top product PABPN1 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:1000
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Shi, Zhang, Wu, He, Wang, Yin, Tian, Li, Cheng: "ALYREF mainly binds to the 5' and the 3' regions of the mRNA in vivo." dans: Nucleic acids research, Vol. 45, Issue 16, pp. 9640-9653, (2017) (PubMed).

  • Antigène
    PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))
    Autre désignation
    PABPN1 (PABPN1 Produits)
    Synonymes
    anticorps OPMD, anticorps PAB2, anticorps PABII, anticorps PABP-2, anticorps PABP2, anticorps Pabp3, anticorps mPABII, anticorps ARABIDOPSIS POLY(A) BINDING 2, anticorps ATPAB2, anticorps F28A23.130, anticorps F28A23_130, anticorps POLY(A) BINDING PROTEIN 2, anticorps POLY(A)-BINDING PROTEIN 2, anticorps poly(A) binding protein 2, anticorps opmd, anticorps pab2, anticorps pabp2, anticorps pabpii, anticorps pabpn1, anticorps Pabpn1, anticorps Poly(A)-binding protein 2, anticorps fb19c03, anticorps wu:fb17e03, anticorps wu:fb18c06, anticorps wu:fb19c03, anticorps zgc:85979, anticorps zgc:92452, anticorps poly(A) binding protein nuclear 1, anticorps poly(A) binding protein, nuclear 1, anticorps poly(A) binding protein 2, anticorps poly(A) binding protein, nuclear 1 S homeolog, anticorps poly(A) binding protein, nuclear 1 L homeolog, anticorps polyadenylate-binding protein 2, anticorps poly(A) binding protein Pab2, anticorps PABPN1, anticorps Pabpn1, anticorps PAB2, anticorps pabpn1.S, anticorps pabpn1.L, anticorps LOC100728725, anticorps pab2, anticorps pabpn1
    Sujet
    This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.,PABPN1,OPMD,PAB2,PABII,PABP-2,PABP2,Epigenetics & Nuclear Signaling,RNA Binding,PABPN1
    Poids moléculaire
    31 kDa/32 kDa/37 kDa
    ID gène
    8106
    UniProt
    Q86U42
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