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PARN anticorps (AA 1-280)

PARN Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6145230
  • Antigène Voir toutes PARN Anticorps
    PARN (Poly A Specific Ribonuclease (PARN))
    Épitope
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-280
    Reactivité
    • 39
    • 9
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 29
    • 10
    Lapin
    Clonalité
    • 32
    • 7
    Polyclonal
    Conjugué
    • 27
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PARN est non-conjugé
    Application
    • 28
    • 13
    • 11
    • 9
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Séquence
    MEIIRSNFKS NLHKVYQAIE EADFFAIDGE FSGISDGPSV SALTNGFDTP EERYQKLKKH SMDFLLFQFG LCTFKYDYTD SKYITKSFNF YVFPKPFNRS SPDVKFVCQS SSIDFLASQG FDFNKVFRNG IPYLNQEEER QLREQYDEKR SQANGAGALS YVSPNTSKCP VTIPEDQKKF IDQVVEKIED LLQSEENKNL DLEPCTGFQR KLIYQTLSWK YPKGIHVETL ETEKKERYIV ISKVDEEERK RREQQKHAKE QEELNDAVGF SRVIHAIANS
     Réactivité croisée
    Humain
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PARN (NP_002573.1).
    Isotype
    IgG
    Top Product
    Discover our top product PARN Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IF,1:50 - 1:100
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    PARN (Poly A Specific Ribonuclease (PARN))
    Autre désignation
    PARN (PARN Produits)
    Synonymes
    anticorps parn-A, anticorps xparn, anticorps DAN, anticorps RGD1565449, anticorps zgc:56067, anticorps 1200003I18Rik, anticorps poly(A)-specific ribonuclease L homeolog, anticorps poly(A)-specific ribonuclease, anticorps poly(A)-specific ribonuclease (deadenylation nuclease), anticorps parn.L, anticorps PARN, anticorps Parn, anticorps parn
    Sujet
    The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PARN,DAN,DKCB6,PFBMFT4,Epigenetics & Nuclear Signaling,RNA Binding,PARN
    Poids moléculaire
    52 kDa/66 kDa/67 kDa/73 kDa
    ID gène
    5073
    UniProt
    O95453
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