PCM1 anticorps (AA 1-260)

N° du produit ABIN6145315

Détail du produit anti-PCM1 anticorps

Antigène: PCM1 (Pericentriolar Material 1 (PCM1))

Épitope: AA 1-260

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: MATGGGPFED GMNDQDLPNW SNENVDDRLN NMDWGAQQKK ANRSSEKNKK KFGVESDKRV TNDISPESSP GVGRRRTKTP HTFPHSRYMS QMSVPEQAEL EKLKQRINFS DLDQRSIGSD SQGRATAANN KRQLSENRKP FNFLPMQINT NKSKDASTSP PNRETIGSAQ CKELFASALS NDLLQNCQVS EEDGRGEPAM ESSQIVSRLV QIRDYITKAS SMREDLVEKN ERSANVERLT HLIDHLKEQE KSYMKFLKKI

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PCM1 (NP_006188.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PCM1

Antigène: PCM1 (Pericentriolar Material 1 (PCM1))

Autre désignation: PCM1 (PCM1 Produits)

Synonymes: anticorps wu:fb30g01, anticorps wu:fb94e03, anticorps wu:fe14f07, anticorps PCM1, anticorps ptc4, anticorps pcm-1, anticorps PTC4, anticorps 2600002H09Rik, anticorps 9430077F19Rik, anticorps C030044G17Rik, anticorps PCM-1, anticorps pericentriolar material 1, anticorps pericentriolar material 1 L homeolog, anticorps pcm1, anticorps PCM1, anticorps Pcm1, anticorps pcm1.L

Sujet: The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene.,PCM1,PTC4,RET/PCM-1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,PCM1

Poids moléculaire: 59 kDa/222 kDa/228 kDa

ID gène: 5108

UniProt: Q15154

Pathways: Stem Cell Maintenance, M Phase, Maintenance of Protein Location